OCAT #1 Flashcards
steroid, slippery
lipophilic
gastric mucosa, cardiac muscle, mast cells, brain
H2
delivered by the post, can be done for later
packaged
acts on other cells
paracrine
activation of degranulation occurs
translocation
blocks response to receptor
antagonist
internal source chemical that calls for response
endogenous
enzyme that removes the carboxyl group
decarboxylase
VMAT2
Vesicular Monoamine Transporter 2
1st messenger introduced to the cell
transduction
connective tissue and mucosal, paracrine
mast cell
increases secretion of gastric acid
Glands
ring structure of histamine
imidazole
protein in granule during degranulation
VAMP
dendritic cells prevent antigen on membrane to trigger T cells
Contact dependent (need interaction between membrane molecules)
prominent in gut for stimulating gastric secretion
Enterochromaffin like (ECL) cells
exchanges protons from inside granule for histamine from cytoplasm
VMAT2 / contra transport
secretes hormones into the blood stream for long distance
endocrine cell
signal is more effective and stable
short distance
intracellular signalling pathway
DNA (transcription), RNA (translation), and Protein (enzymes and receptors)
sent out from sending cell to target cell
release
acts on self, spreads cancer
autocrine
promotes vasodilatation, causes edema
Vasculature
how ligands binding to receptors bring about an effect to a system
recognition, transduction, response
increase in size and loss of granule staining
activated mast cell
stops molecule from continuing signalling event
termination
pushing system to see what it does
functional
degradation termination intracellular
methyltransferase
fluorescent tagged antibodies
microscopy