OC

Question 1

Definition

Answer 1

Obstetric liver condition that causes a build up of bike acids and liver dysfunction. Chloeostasis due to high levels of Eostrogen

Question 2

Physiology

Answer 2

Liver cells are unable to hold the enzymes which then leak into the blood stream.
Bile acids play a role in digestion and help break down food. The bile acids leak into the blood and can cause teratogenic effects.

Question 3

Signs and symptoms

Answer 3

Pruritus (nocturnal) Raised bile acids and abnormal LFTS. Right upper quadrant pain
, pale stools, jaundice
UTI

Question 4

Risk factors

Answer 4

Multiple pregnancies
Subsequent pregnancies
Make sure to rule hepatitis, liver ultrasound

Question 5

Complications

Answer 5

Gall stones, recurrent OC, contraceptive chloeostasis, vitamin k deficiancy, pph liver failure

Question 6

Fetal comp cations

Answer 6

Bile acids cause Vaso constriction of the placental veins causing premature delivery and still birth, meconium

Question 7

Management

Answer 7

Weekly LFTS, bile acids
Antihistamines for itching and calmoline lotion 
Vitamin k orally 
Regular USS monitor movements
Risk of pph so active third stage