Obstructive vs. Restrictive lung disease Flashcards
obstructive is characterized by?
- airflow obstruction
- increased airway resistance
- often affects expiratory flow rate
restrictive lung disease is characterized by?
- reduced lung compliance
- reduced thoracic compliance
- often affects inspiratory volume
obstructive lung disease (OLD) includes:
- chronic bronchitis
- emphysema
- bronchiectasis
- asthma (also restrictive)
- CF
Restrictive lung disease
- interstitial lung disease
- idiopathic pulmonary fibrosis (IPF)
OLD - epidemiology
3rd leading cause of death in US
- smoking is primary risk factor
- 11th year demonstrating more women die from diagnosis of COPD than men
OLD radiographs
- flattened diaphragm
- hyperinflated lungs due to air trapping
- enlarged heart with enlarged right ventricle
- barrel chest
OLD potential consequences
- destruction of lung tissue resulting in emphysema
- inflammation of airways
- hypoxemia
- dysrhythmias
- sleep disorders
- repeated infections
- build up of secretions
OLD consequences continued
polycythemia
- adaptation to chronically low 02 - be careful giving more 02 –> reduces hypoxic drive to breathe
- sluggish blood flow
- right side heart failure
- resistance to air flow -> inc. work of breathing
- normal or increased lung capacity
Chronic bronchitis:
Diagnosis and causes
Greater than 3 months of productive cough most days in at least 2 consecutive years
causes:
- irritation of bronchial tree (smoke, particles)
- genetics
- respiratory infections
symptoms of OLD
- secretion production
- reduced cilia action leading to build up of secretions and bacteria
- repeated infection, pneumonia
- hypoxemia
Emphysema- End stage COPD
Definition and actions
Abnormal, permanent increased size of air sacs distal to terminal bronchioles by destruction of alveolar walls
- alveolar destruction
- over inflation of lungs, cannot empty
- emphysematous bull
- chronic hypoxia and hypercapnia (excessive CO2) in blood
Restrictive lung disease (RLD) includes?
decreased expansion of lungs
- decreased total lung capacity
- hypoxemia
Examples of RLD
- disease of pleura
- disease of chest wall (kyphoscoliosis, obesity)
- extrapulmonary mass restricting expansion of lungs
causes of RLD?
- stiffening of lung tissue preventing expansion
- structural limitations preventing lung inflation (kyphoscoliosis)
- interstitial lung disease
- pleural abnormalities “trapped lung”
- mass
- lupus
- pmneumothorax
- connective tissue disease: scleroderma
- radiation therapy
- idiopathic pulmonary fibrosis (IPF)
Idiopathic pulmonary fibrosis
onset: middle age (50-70)
- 4-5 yrs life expectancy
- increased respiratory rate (30-40)
- hypoxemia, cyanosis –> give 02
- treat inflammation before it turns into fibrosis (corticosteroids)