Obstructive respiratory

Question 1

Acronym?

Answer 1

CABG-XL

cromones
anti cholinergic 
Beta adrenergic agonist
glucocorticoids
xanthine derivatives
leukotrin inhibitors

Question 2

Beta adrenergic agonists

• acts on
• purpose
• mechanism of action
• side effects

Answer 2

B2 receptors
cause relaxation and bronchodilation
inhalation - fast acting
inhalers and nebulizers
airway irritation, nervousness, increased HR

Question 3

Leukotrin inhibitors

• acts on
• purpose
• mechanism of action
• side effects

Answer 3

mediate airway inflammation
inhibit lipoxygenase enzyme
combined with glucocorticoids for optimal COPD and asthma treatment

Question 4

Anti - cholinergic

• acts on
• purpose
• mechanism of action
• side effects

Answer 4

block muscarinic cholinergic receptors
prevents ACH induced broncho-constriction
drug of choice for COPD, chronic bronchitis
inhaled
dry mouth, constipation, urinary retention, blurred vision

Question 5

xanthine derivatives

• acts on
• purpose
• mechanism of action
• side effects

Answer 5

CNS stimulant for reversible airway obstruction
works on smooth muscle cells to bronchodilate, and anti inflammatory effect
oral
nausea, confusion,
serious life threatening effects
avoid long term use
not used frequently anymore.

Question 6

cromones

• acts on
• purpose
• mechanism of action
• side effects

Answer 6

can be used prophylactically to treat asthma in children
inhibits inflammatory mediators
nasal spray
free of side effects
infrequently used

Question 7

Glucocorticoids

• acts on
• purpose
• mechanism of action
• side effects

Answer 7

most effective for controlling asthma
anti inflammatory effects by inhibiting pro-inflammatory proteins
thrush, DM, HTNf
avoid long term oral use