Obstructive and restrictive Pulmonary Disease Flashcards
What are the characteristics of COPD
- progressive airway obstruction that is not fully reversible
- gas exchange is normal
- always hyperinflated (difficulty getting air out)
- Decreased elastic recoil
- age of onset: middle aged to older adults
COPD Rx
- Pharmacological FOCUS:
1. smooth mm relaxation
2. reduce airway inflammation - O2 therapy: but not for pts with pulmonary HTN, CHF
What is bronchitis
What is the key feature of bronchitis
inflammation of the lining of your bronchial tubes. Key feature is excess mucus production in bronchioles
Main cause of emphysema
smoking
Result of emphysema
Destruction of air spaces distal to the terminal bronchiole + destruction of alveolar septa
- causes merging of alveoli into larger air spaces - which leads to decreased surface area for gas exchange
loss of airways and capillaries as well
Emphysema Impact
Difficulties with exhalation
- Damaged alveoli = old air becomes trapped
- Decreased space available for O2-rich new air
- Hyperventilation flattens diaphragm
- now at mechanical disadvantage
Emphysema Rx
Can slow down progression but can’t reverse damage
What is bronchiectasis
irreversible destruction (necrosis) + dilation of airways with chronic bacterial infection
Bronchiectasis causes
CF
TB
Endobronchial tumour
Bronchiectasis characteristics:
- excess mucus leading to SOB
- eventually alveoli replaced with scar tissue - due to chronic inflammation
Bronchiectasis Rx
- bronchodilators, antibiotics, corticosteroids
- secretion clearance
What is interstitial lung disease
Progressive scaring leading to stiffness and decreased lung compliance (not airway obstruction)
Interstitial lung disease S&S
- dyspnea
- severe O2 desaturation (cyanosis)
- clubbing of fingers and toes
- decreased exercise tolerance
Interstitial lung disease Rx
- O2 therapy
- lung transplant
- pulmonary rehab
- Cessation of exposure (known cause)
What causes pulmonary fibrosis
2/3 no know cause
1/3 TB
Inhaling harmful particles
Pulmonary fibrosis pathology
Fibrosis = scaring in lungs
Damage to bronchioles and alveoli - greatly decreased gas exchange
Pulmonary fibrosis Rx
- Radiation therapy
- Meds
Pneumoconiosis is also referred to as ___
coal worker’s lung