Obstructive Airway Disorders Flashcards
Obstructive Lung Disorder characterized by
an increased airway resistance
FEV1/FVC ratio in obstructive disorders is
decreased
Obstructive disorders includes
chronic bronchitis, asthma, emphysema
chronic bronchitis
inflammation, mucus secretion, obstruction of airway
asthma
hypersensitivity, mucus production, bronchoconstriction, obstruction of air flow
emphysema
enzyme digestion of proteins like elastin
smaller the radius
larger the resistance
Underlying pathophysiology of asthma
IgE and mast cell degranulation, causing inflammatory mediators(histamines) to be released, causing smooth muscle contraction, increased secretions
chronic inflammatory disorder of airways
asthma
inflammation of bronchi
bronchitis
persistent abnormal dilation of bronchi that is frequently associated with bronchitis
bronchiectasis
inflammatory obstruction of the bronchioles, smooth muscle constriction
bronchiolitis
two things form COPD
chronic bronchitis and emphysema
abnormal permanent enlargement of gas exchange airways accompanied by destruction of alveolar walls
emphysema
primary emphysema
inherited deficiency of a1-antitrypsin