Obstetrics Flashcards
What is gestational diabetes?
Any degree of glucose intolerance with onset or first recognition during pregnancy.
Name 5 risk factors for GD.
BMI > 30
Asian ethnicity
Previous GD
1st degree relative with diabetes
PCOS
Previous macrosomic baby
What investigation is used for gestational diabetes?
Oral glucose tolerance test
When do you test for GD in the pregnancy?
Between 24 and 28 weeks of pregnancy
If you had diabetes in a previous pregnancy, when should you be tested for GD in your next?
At the booking appointment
What is the first line treatment for GD in pregnancy?
Metformin
What is the second line treatment for GD?
Glibenclamide
What is the treatment for GD if not controlled with metformin and glibenclamide?
Insulin basal bolus routine
What are the foetal complications associated with GD?
Macrosomia
Shoulder dystocia
Still birth at term
Hyperinsulinemia
What causes macrosomia in GD?
Glucose is able to pass across the placenta but insulin cannot.
Therefore the baby gets too much glucose leading to macrosomia
Name 4 maternal complications of GD.
Miscarriage
DKA
Hypoglycaemia
Progression of retinopathy
Premature labour
Pre-eclampsia
What is the pathophysiology of pre-eclampsia?
Abnormal invasion of the trophoblast into maternal spiral arterioles. Causing high vascular resistance and poor perfusion of the placenta.
Name the 5 key symptoms of pre eclampsia.
Headache
Visual disturbance
Nausea and vomiting
Upper abdo pain
Oedema
What are the signs of pre-eclampsia?
Brisk reflexes
Reduced urine output
Name 3 risk factors for pre-eclampsia.
Family history of pre-eclampsia
Pre-existing hypertension
Diabetes
First pregnancy
Obesity
Name 3 maternal complications of pre-eclampsia.
Pulmonary oedema
Renal failure
Stroke
Eclampsia
HELLP syndrome
What does HELLP stand for?
Haemolysis, Elevated liver enzymes, low platelets.
Foetal complications of pre-eclampsia?
Intrauterine growth restriction
Placental abruption
Still birth
What is the medical management of pre-eclampsia?
Aspirin from 12 weeks in high risk patients
Labetalol
Nifedipine
Methyldopa
Symptoms of HELLP syndrome?
Bleeding
Fatigue
Malaise
RUQ pain (liver going wrong)
N&V
Swelling
Blurred vision
How does a concealed abruption present?
Woody uterus
What is placenta praevia?
A low lying placenta close to or lying over the internal OS.
Name 5 risk factors for placenta praevia.
Previous C-section
High parity
Over 40
Multiple pregnancies
Previous placenta praevia
What is placenta accreta?
The placenta attaches beyond the endometrium of the uterus and into the myometrium.