Obstetric Pharm

Question 1

During pregnancy, does gastric absorption slow or increase?

Answer 1

slow- oral medication takes longer to take effect

Question 2

What makes IV administered medication pass quickly through the maternal system?

Answer 2

increase in hepatic metabolism and increase in renal excretion

Question 3

What is magnesium sulfate classified as?

Answer 3

electrolyte

Question 4

When is magnesium sulfate used in pregnancy?

Answer 4

severe hypertension lasting more than 15 minutes with preeclampsia or seizure in 20 weeks of greater of gestation

Question 5

What are the side effects of magnesium sulfate?

Answer 5

drowsiness, respiratory depression, hypotension, bradycardia with rapid administration

Question 6

What is calcium chloride classified as?

Answer 6

electrolyte

Question 7

What is calcium chloride an antidote for?

Answer 7

magnesium sulfate overdose

Question 8

What are the adverse effects of calcium chloride?

Answer 8

nausea, vomiting, syncope, bradycardia, dysrhythmias

Question 9

How is calcium chloride administered?

Answer 9

slow IV push

Question 10

What is valium/diazepam classified as?

Answer 10

benzodiapine

Question 11

When is diazepam/valium indicated in pregnant women?

Answer 11

Eclampsia when the pt’s seizure do not respond to magnesium sulfate

Question 12

What are the adverse of valium/diazepam?

Answer 12

nausea, vomiting, respiratory depress and hypotension

Question 13

What is Diphenhydramine classified as?

Answer 13

antihistamine

Question 14

How is diphenhydramine used in pregnancy?

Answer 14

sedative and antiemetic (nausea/vomiting),treats hyperemesis gravidarum

Question 15

What is the classification of ondansetron?

Answer 15

antiemetic (nausea and vomiting

Question 16

What are the adverse effects of ondansetron?

Answer 16

QT polongation

Question 17

How does oxytocin work?

Answer 17

naturally occuring pituitary hormone that triggers uterine contractions by acting on smooth muscle

Question 18

What is oxytocin used for?

Answer 18

only to control severe postpartum hemorrhage after all products are expelled from the uterus

Question 19

What are the adverse effects of oxytocin?

Answer 19

nausea/vomitting, seizures, cardiac dysrhythmias and anaphylaxis

Question 20

What can happen if oxytocin is given in excess?

Answer 20

coma, uterine rupture and hypertension

Question 21

Indications for magnesium sulfate

Answer 21

Pre-eclampsia
Eclampsia

Question 22

What is Pitocin

Answer 22

synthetic oxytocin, controls hemorrhaging and sustains uterine contractions

Question 23

Contraindications of Pitocin

Answer 23

do not administer until the baby and placenta has been delivered

Question 24

Dose of Pitocin

Answer 24

10-40 units in 1L of solution