Obstetric Pharm Flashcards

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1
Q

During pregnancy, does gastric absorption slow or increase?

A

slow- oral medication takes longer to take effect

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2
Q

What makes IV administered medication pass quickly through the maternal system?

A

increase in hepatic metabolism and increase in renal excretion

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3
Q

What is magnesium sulfate classified as?

A

electrolyte

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4
Q

When is magnesium sulfate used in pregnancy?

A

severe hypertension lasting more than 15 minutes with preeclampsia or seizure in 20 weeks of greater of gestation

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5
Q

What are the side effects of magnesium sulfate?

A

drowsiness, respiratory depression, hypotension, bradycardia with rapid administration

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6
Q

What is calcium chloride classified as?

A

electrolyte

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7
Q

What is calcium chloride an antidote for?

A

magnesium sulfate overdose

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8
Q

What are the adverse effects of calcium chloride?

A

nausea, vomiting, syncope, bradycardia, dysrhythmias

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9
Q

How is calcium chloride administered?

A

slow IV push

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10
Q

What is valium/diazepam classified as?

A

benzodiapine

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11
Q

When is diazepam/valium indicated in pregnant women?

A

Eclampsia when the pt’s seizure do not respond to magnesium sulfate

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12
Q

What are the adverse of valium/diazepam?

A

nausea, vomiting, respiratory depress and hypotension

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13
Q

What is Diphenhydramine classified as?

A

antihistamine

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14
Q

How is diphenhydramine used in pregnancy?

A

sedative and antiemetic (nausea/vomiting),treats hyperemesis gravidarum

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15
Q

What is the classification of ondansetron?

A

antiemetic (nausea and vomiting

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16
Q

What are the adverse effects of ondansetron?

A

QT polongation

17
Q

How does oxytocin work?

A

naturally occuring pituitary hormone that triggers uterine contractions by acting on smooth muscle

18
Q

What is oxytocin used for?

A

only to control severe postpartum hemorrhage after all products are expelled from the uterus

19
Q

What are the adverse effects of oxytocin?

A

nausea/vomitting, seizures, cardiac dysrhythmias and anaphylaxis

20
Q

What can happen if oxytocin is given in excess?

A

coma, uterine rupture and hypertension

21
Q

Indications for magnesium sulfate

A

Pre-eclampsia
Eclampsia

22
Q

What is Pitocin

A

synthetic oxytocin, controls hemorrhaging and sustains uterine contractions

23
Q

Contraindications of Pitocin

A

do not administer until the baby and placenta has been delivered

24
Q

Dose of Pitocin

A

10-40 units in 1L of solution