Obesity & Orlistat Flashcards
What classifies as obese, and overweight?
BMI >30 = obese
BMI 25-29.9 = overweight
What measurement is a good indication for CVD?
Waist to height ratio
What medications can cause weight gain?
Sulfonylureas - gliclizides, glipizide
Steroids
Anticonvulsants - valproate
Pizotifen
Antidepressants
Insulin
Contraceptives
What should the intended exercise routine be to aid a patient in losing weight?
150mins of moderate exercise a week
OR 75mins of vigorous exercise a week
What activities classify as moderate exercise?
Walking
Cycling
Gardening
What activities classify as extreme exercise?
Any activity that leaves you very out of breath
Where can pharmacists refer patients who are wanting to lose weight?
Weight loss services, e.g. Weight Watchers, Slimming World, etc
What are the 2 types of orlistat available?
Orlistat 120mg TDS POM
Orlistat 60mg TDS OTC
When do you refer a patient who is taking orlistat?
If they have had no result whilst on orlistat for >12 weeks (3months)
What are some side effects of orlistat?
Fatty stools
Discharge
Flatulence
Sudden bowel movements
How does orlistat work?
It inhibits GI lipases, preventing the absorption of fats
What drugs can orlistat interact with?
Ciclosporin
Levothyroxine
Anticoagulants
Amiodarone
Antiepileptics
Fat-soluble vitamins (D/E/K)
Antiepileptics
Contraceptives
What is the GLP-1 agonist which can also be used for weight loss?
Liraglutide
What does the CV (Mediterranean) diet consist of?
Reduced saturated fats/sugars
2 portions of fish a week, including 1 portion oily fish
Eat 5 portions of fruit/veg a day
Eat 4-5 portions of unsalted nuts/seeds/legumes a week
Eat whole-grains
