Atrial Fibrillation Flashcards

1
Q

What causes AF?

A

Disrupted electrical signals in the heart, causing an irregular heart beat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the 3 parameters which AF can be classified by?

A
  1. Heart rate - tachycardia/bradycardia
  2. Origin of electrical impulses - atria/ventricles
  3. Time
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the 2 arrhythmias called which originate in the atria, and in the ventricles?

A

In the atria = supraventricular arrhythmia
In the ventricles = ventricular arrhythmia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is absent on an ECG in an AF patient?

A

P wave, due to the disrupted depolarisation of the patients atria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What can cause AF?

A

Damage to heart
Drugs - caffeine, alcohol, thyroxine, B2 agonists
Non-cardiac causes - hyperthyroidism, acute infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the tool used to measure someones bleeding risk?

A

HASBLED scoring system
Now some places are using the ORBIT tool

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is given to reverse the effects of warfarin?

A

K+ supplements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the CHA2DS2VASc tool? How do you interpret a patients score?

A

It measures a patients stroke risk.

1 point = no therapy/aspirin considered
>2 points = warfarin/DOAC given (high risk)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What types of drug classes should AF patients avoid?

A

NSAIDs
SSRIs
antiplatalets

These can all increase their bleeding risk while they are on anticoagulation therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What anticoagulants are given to AF patients to help reduce their stroke risk?

A

DOACs, e.g. apixaban, rivaroxiban, edoxaban

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the treatment of rhythm control in AF?

A

Stable AF - flecainide (no IHD), or amiodarone (with IHD)

Unstable - DC shock given

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the 1st line treatment for rate control in AF?

A

B-blocker
OR rate-limiting CCB, e.g. verapamil/diltiazem

Digoxin could also be given as monotherapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Why should you never give a b-blocker with a CCB in AF?

A

Because it can increase the patients risk of a heart attack

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the treatment for bradycardia?

A

Atropine 500mcg IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the treatment for tachycardia?

A

Unstable - synchronised DC shock
Stable - adenosine 6mg IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What monitoring is needed for AF?

A

INR (patient must be between 2-3)
Symptoms of AF
HR
ECG

17
Q

What are the benefits of using a DOAC compared to warfarin?

A

Good safety
Fixed dosing regimen
Less interactions

18
Q

What are the other alternative options of treatment for AF?

A

Class 1 - Na+ channel blockers
1A - quinidine, procainamide
1B - lidocaine, phenytoin
1C - flecainide

Class 2 - B-blockers

Class 3 - K+ channel blockers
Amiodarone, soltalol

Class 4 - Rate-limiting CCBs
Verapamil, diltiazem

Class 5 - adenosine, digoxin

19
Q

What is the difference between dabigatran, and the other DOACs?

A

Dabigatran is the only direct thrombin inhibitor.
The rest are oral factor Xa inhibitors.