Inflammatory Bowel Disease

Question 1

What 2 conditions fall under inflammatory bowel disease?

Answer 1

Crohns disease
Ulcerative colitis

Question 2

What is the difference between crohns disease and ulcerative colitis?

Answer 2

Crohns disease: inflammation of colon with skip lesions

Ulcerative colitis: inflammation/lesions only present in the terminal (descending) part of the colon

Question 3

What are the symptoms of IBD?

Answer 3

Abdominal pain
Passage of mucus
Perianal disease
Bloody stools
Diarrhoea

Question 4

What tests are performed which can confirm a diagnosis of IBD?

Answer 4

Endoscopy
Colonoscopy
White patches will indicate inflamed tissue

Question 5

What are the 4 phases of IBD?

Answer 5

1. Initiating triggers
2. Acute intestinal inflammation
3. Chronicity
4. Destruction of tissue leading to complications

Question 6

Which aminosalicylates can be given for active/maintenance of ulcerative colitis?

Answer 6

Mesalazine
Sulfasalazine

Question 7

When are steroids given in IBD?

Answer 7

Relapsing of ulcerative colitis or crohns disease

Question 8

Which immunosuppressants are given for maintenance of ulcerative colitis/crohns disease?

Answer 8

Azathioprine
6-mercaptopurine
Methotrexate
Cyclosporin

Question 9

What is faecal microbiota transplantation?

Answer 9

Processing stool of a donor and transferring it into an IBD patient