Obesity Flashcards

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1
Q

What lifestyle factors impact health

A
  • drug use
  • diet
  • exercise
  • use of sunscreens
  • use of condoms
  • attendance at screening/health checks
  • hygiene
  • use of safety belts and helmets
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2
Q

Why is it hard to change behaviour

A
  • giving up something pleasurable can be difficult
  • changing routines is usually difficult
  • habits and addictions are hard to modify
  • motivation to change fluctuates
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3
Q

What is locus of control

A
  • generalised expectancy that rewards are controlled by external forces or by ones own behaviour (internal (you can control it) vs external (you cannot control it))
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4
Q

What is the health belief model

A

action is a function of perceived likelihood of illness, its seriousness and costs and benefits of action

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5
Q

what are the stages of change that people go across when thinking of changing behaviour

A
  • Pre -contemplation
  • contemplation
  • preparation
  • action
  • maintenance or relapse
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6
Q

What is the efficacy of lifestyle interventions determined by

A
  • strength of the drive for the unhealthy behaviour
  • effort required
  • target population - motivation, social factors, personal characteristics ,biological factors
  • efficacy of supportive medication
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7
Q

list some complications of obesity

A
  • pulmonary disease - abnormal function, obstructive sleep apnea, hypoventilation syndrome

Nonalcoholic fatty liver disease

  • steatosis
  • steatohepatiits
  • cirrhosis

Gallbladder disease

gynaecological abnormalities

  • abnormal menses
  • infertility
  • PCOS

Osteoarthritis

stroke

cataracts

coronary heart disease

  • diabetes
  • dyslipidaemia
  • hypertension

Severe pancreatitis

Cancer

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8
Q

What are the benefits of weight loss

A
  • Can reduce blood pressure
  • can prevent onset of T2DM
  • reduce blood glucose and LDL cholesterol
  • improve sleep apnoea
  • benefits start to accrue when 5-10% of initial body weight is lost
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9
Q

What is the cause of obesity

A
  • more energy in and less energy out leads to more energy stored and converted to fats
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10
Q

What is the basal metabolic rate for women

A

1200-1600kCal per day

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11
Q

what is the resting metabolic rate

A

the energy you use when you don’t do anything

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12
Q

Describe what happens to the resting metabolic rate

A
  • increases with increased muscle mass
  • declines with age
  • declines during restriction of energy intake
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13
Q

What determines our body weight

A

Interaction of

  • behaviour
  • genes
  • environment
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14
Q

What are some strategies for weight loosing

A
1, Self-monitoring 
2, Stimulus control 
3, Goal setting 
4, Cognitive restructuring 
5, Incentives
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15
Q

How do you self monitor in weight loosing

A
  • food diaries - record type and amount of food eaton and times, places and feelings associated with eating
  • pedometers to monitor physical activity
  • scales to monitor body weight regularly - essential for any progress
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16
Q

How can you use stimulus control in weight loosing

A

Identify and modifying environmental cues to eating

  • limit eating to kitchen
  • remove snacks from TV room
  • keep tempting food out of sight
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17
Q

How does goal setting work in weight loss

A
  • 5% weight loss over 6 months

- loose a 1lb a week is a realistic goal

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18
Q

How does cognitive restructuring work in weight loss

A

identifying and challenging self defeating thoughts and counterproductive beliefs

19
Q

how do incentives help weight loss

A
  • agreements with HPs, friends, slimming group

- rewards and praise for achieving goals

20
Q

What are the predictors of success of weight loss

A
  • diet and activity
  • 400kcal/day in activity
  • average 5 eating episodes day including breakfast
  • weighing yourself at least once a week
21
Q

What are the physical activity recommendations

A
  • 30 minutes moderate activity on 5 or more days a week
  • up to an hourly may be needed to prevent obesity
  • up to 90 minutes/day to maintain weight reduction
22
Q

Who can have orlistat

A
  • greater than 12 years old
  • BMI over 30 years old
  • or BMI >27 with risk factors such as hypertension, diabetes, dyslipidemia
23
Q

How do you take orlistat

A

120mg TDS with meals containing fat

24
Q

Whats another version of orilstat

A

Alli

25
Q

Who can take Alli

A
  • 18 years old

- for weight loss when used with rescued calorie and low fat diet

26
Q

What is the dosage of Alli

A
  • 60mg TID with meals containing fat
27
Q

What are the side effects of orlistat

A
  • Diarrhoea
  • Steatorrhoea
  • reduce intake of fat soluble vitamins in a small proportion of users
28
Q

What fat is good

A
  • subcutaneous fat seems protective

- internal fat e.g. liver fat is a problem

29
Q

What is the Atkins diet

A
  • max 20 grams of carbohydrates a day

- protein and fat as much as you like

30
Q

What are some other dietary approaches to weight loss

A
  • Low glycemic index diets
  • low calorie diets with and without meal replacement
  • intermittent fasting
31
Q

What is a low GI index diet

A
  • GI is the effect of carbohydrates on postprandial glycaemia
32
Q

Who is the low GI index diet used for

A
  • suggested for CHD and diabetes risk reduction but the evidence is weak
33
Q

Why does the glycemic index have a mixed result

A
  • Large individual difference in triglyceride, glucose and insulin response to indentical meals
  • gut microbiome affected lipemia (more than food content) but not glycemic
  • genes play some role for glucose but not for lipids and C-Peptide
34
Q

What is the 5:2 diet

A

2 non consecutive days on 500/600 kcal

  • then rest of the day can eat food
  • seems to make Intermittent fasting easier
35
Q

Name some appetite suppressant medication used for weight loss

A
  • Mehtylcellulus
  • Amphetamine derivatives - withdrawal
  • Sibutramine - Withdrawn
  • Rimonabant - Withdrawn - risk of suicide
  • GLP-1 agonists are successful in diabetes and effective in weight loss
36
Q

What is Liraglutide

A
  • GLP-1 agonist
  • have to be injected
  • recommended by NICE as part of a tripe therapy for diabetes and has been used for weight loss
37
Q

How do GLP-1 agonists work

A
  • daily subcutaneous injection

- makes patients fell more full and delays the speed that the stomach empties

38
Q

What are the side effects for GLP-1 agonists

A
  • some nausea and vomiting but not bad enough to make them stop taking the medication
  • reports of pancreatitis
39
Q

who is gastric surgery considered in

A
  • Considered in BMI of greater than 40 or greater than 35 with co-morbidities
  • e.g. T2DM, sleep apnoea, high blood pressure or arthritis requiring joint replacement
40
Q

What are the two types of surgical procedures for weight loss

A
  • restrictive

- restrictive and malabsorption

41
Q

Name a restrictive and malabsorption procedure

A
  • Roux-en Y bypass
42
Q

Name a restrictive procedure

A
  • gastric band
43
Q

What are the possible aftermath to a surgical weight loss procedure

A
  • Skin flaps reducing aesthetic gain
  • suicides
  • post surgery addictions to gambling, alcohol and narcotics - but this is rare
44
Q

What is a gastric aspiration

A
  • tube in stomach, button in abdomen, apparatus to carry along
  • chew slowly
  • 1/3 of stomach contents flushed into loo after meal over 5-10 minutes