Obesity Flashcards
What are the causes of obesity?
The fat computer programmer sit in his cubical all day chugging coconut milk. His boss is always yelling about deadlines. And sometimes his imaginary friend Pedro comes to visit showing him how to inject steroids with insulin needles. Genetically he is a preditor and shouts “Fuck The Oakleys”. To top it all of his gf isnt on contraceptives.
- High calorie diet
- No activity
- Stress
- Medications
- Antipsychotics, Contraceptive, steroids, insulin, sulfonylureaus
- Gentics
- Prader-Willi, FTO gene
Obese class 1,2,3 BMI
30-34.9
35-39.9
> = 40
Management of obesity 1
Management of obesity 2
Diet to lose fat
Reduce calorie intake
500-100 kcal/day
goal 800-1200
Exercise
150 minutes
Behavior stuff?
- Support group
- Realistic goals
- SMART/FITT
- Shitty goal- I want to lose weight
- SMART goal- eat 1500 calories per wk day and excercise for 30 minutes everyday loss 10 lbs
- Self monitoring
Antiobesity Agents
Orlistat
DIs?
Vit K?
Take MVi 2 hours before or after
120 mg tid rx
>= 12
60 mg TID OTC
Seperate from levothyroxine by 1 hour
Monitor INR with vit K antagonist
reduces amiodarone efficacy
Lorcaserin
Dose
DI
AE
10 mg BID BMI > 30 BMI 27 with other comorbidities
Nausea headache, fatigue dizzy
Not to be used if pregnant, Valv HD, ESRD, caution in CHF, HTN, hyperprolactinemia
Phentermine/topiramate ER
Initial dose 3.75/23 mg for 14 days then 7.5/46 daily
may increase to 11.25/69 mg daily for 14 days
15/92 daily
Not to be used if pregnant, glaucoma, hyperthyroidism, MAOIs, suicide, moderate high CVD
Caution with renal or haptic impairment
Bupropion/naltrexone dosing
Wk1 - 1 tab am
2 1 tab bid
3 2 am 1 pm
4 2 tabs BID
Dont use in uncontrolled HTN, Seizure, bulimia, anorexia, prgnant
Caution in renal hepatic impairment
Liraglutide
Start with 0.6 mg SQ daily and increase by 0.6 weekly to dose of 3 mg
Lots of nausea,
No in thyroid cancer, pregnant, pancreatitis,
Renal
Dosing summary
When do you refer for bariatric surgery?
BMI >= 40 or 35 with additional comorbidiies
Very successful
Many types of bariatric surgery
Bands, Sleeve, bypass,
All reduce stomach volume