Ischemic Heart Disease Flashcards
Ischemic Heart Disease is also know as?
Coronary heart disease, or coronary artery disease
Ischemic heart disease is primarily cause by?
Artherosclocrosis
Artherosclocrosis results from?
From decreases blood flow to the heart and leads to reduced oxygen delivery
When does angina occur?
Demand > Supply
How does IHD present itself?
- Chest pain or pressure
- Discomfort in
- Neck
- Jaw
- Shoulder or arm
- Pain accumanied with nausea or vomiting
Female patients often describe symptoms as?
Indigestion or acid feeling
IHD occurs in women or men more?
men
What forms when someone has Artherosclorosis?
A plaque forms this is what causes the reduced oxygen
Stable angina is classified as pain lasting?
less than 10 minutes
Angina lasting between 10-15 minutes is known as?
Variant
Unstable angina is when the pain lasts for?
more than 20 minutes
Chest pain is _____ during stable angina
predictable
The onset of variant angina is?
gradual
In unstable angina the pain is _____ and there is ____ onset
severe and the onset is new
Stable angina or occurs upon?
Exertion
Variant angina often occurs ____ and at ____
in the morning and at rest
Unstable angina occurs ____ or at _____
exertion or at rest
What are the modifiable risk factors of Ischemic heart disease
The Fat Smoker Checked His Glucose Monitor and his head began to BOIL he then Drank some BEER
- Tobacco smoking
- Hypercholesterolemia
- DM
- HTN
- Obesity
- Alcohol
What are the non-modifiable risk factors for IHD?
45 + 10 +10
- Men > 45
- Females >55
- FH of CVD
- First degree relative
- Females < 65
- Men <55
Beta blocker ____ HR
_____ Cardiac contractility
_____ Systolic Pressure
____ Left Ventricle Volume
Decrease all
What is 1st line therapy for IHD?
Beta blockers
What are the 3 preferred beta blockers?
Carvedilol, metoprolol succinate, bisoprolol
Beta Blockers are contra indicated with patients with?
Severe bradycardia (<60 bpm)
AV conduction med Digoxin, verapamil, diltiazem
Asthma, COPD, DM, HF
CCBs are second line for IHD decrease?
HR
Amlodipine is a preferred ____
CCB
CCBs should not be used when?
Digoxin or BB
HF
same as BBs
You should not use ____ in patients with variant angina
BBs
What is the 2nd/3rd line for IHD?
Nitrated long acting
What do nitrates do?
WHat are they limited by?
Decrease wall tension, preload and oxygen demand
Limited in tolerance development thats why you need 8-12 hours of non nitrate therapy
Nitrates should not be used with?
Patients wiht _____ hypotension
and cause ____ depletion
PDE-5 inhibitors
severe hypotension and can cause volume depletion
All patients should use ____ release nitroglycerin
IR
How do you educate the patient to use nitroglycerin tablets?
- ___ ___ when administering the medication, have phone close by.
- Place __ tablet under the tongue and allow it to dissolve.
- If pain persists after ___ minutes, administer the 2nd tablet.
- Call ____ after administering ___ tablet.
- May administer a 3rd tablet if pain continues ____ after the 2nd tablet for a max of ___ tablets in 15 minutes.
- Sit down
- 1 tablet
- 5 minutes
- Call 911 after admin of 2nd tab
- 5 minutes, max of 3 tabs in 15 minutes
- If a new bottle, prime pump with ____ test sprays
- When pain occurs, spray 1-2 sprays into mouth while sitting down and phone close by. Do not ___, ____ or spit out the spray for at least 5- 10 minutes.
- Wait 5 minutes, if pain persists may spray a ___ spray and call 911
- Replace cap on the bottle
- If bottle is not used more than 6 weeks must prime again
- 5-10
- swallow or inhale
- 3rd
Ranolazine is ____ line for IHD and it has no effect on?
2nd 3rd line
no effect on HR or BP
Ranolazine contraindications
- Hepatic cirrhosis
- Use with CYP3A inducers
- Rifampin, carbamazepine, phenytoin, phenobarbital
Revascularization should be used when?
- Max tolerable meds are used and symptoms are still occuring
- High risk patients multiple comorbidities
What is the antiplatelet therapy used after PCI?
Aspirin 81 mg forever
Clopidogrel 75 mg daily, ticogrelor 90 BID or Prasugrel 10 mg for 1 year
Want to treat Bp if it is >?
140/90
Consider ____ screening in High risk patients as well as?
DM
Depression and Kidney function
CCBs like ____, ___ and ____ should be first choice for ____ angina
Verapamil, diltiazem and nifedipine
for variant angina