OA Flashcards
1
Q
OA
A
(DJD- Degenerative Joint Dz)
- most common joint dz
- non-infl
- lack of systemic sx’s
- pain relieved by rest/ morning joint stiffness is brief
- oligoarticular
- generalized
- aging!
2
Q
OA- bony changes
A
- crepitus
- malalignment/instability
- limited ROM
- joint line tenderness
- cool effusions
- spasm or atrophy of adj m’s
3
Q
OA- risk factors
A
- age, obesity, genetics, menopause
- m strength, proprioception, repetitive use, joint configuration, trauma
4
Q
OA- most common joints involved?
A
- cervical spine, lumbar spine
- 1st CMC, PIP, DIP
- hip, knee
- 1st MTP
5
Q
OA- radiographic findings
A
- joint space narrowing
- osteophytes and marginal lipping
- subchondral thickening
- bone cysts (from microfractures)
- joint mice
6
Q
OA- pathogenesis
A
- degeneration of articular cartilage
- chondrocytes= stress
- damage from physical forces- chondrocytes release degradative enzymes; inadequate repair response- drop out, cartilage loss, bone changes, loose bodies
- defective cartilage fails under normal joint loading (type II collagen gene defect)
7
Q
OA- subchondral bone
A
= new articular surface
- friction, bone eburnation
- sclerosis, small fracture, cyst
- altered bone contour, lipping
- osteophyte
8
Q
OA hereditary
A
- sum of mult genes- risk of OA
- heterogeneous
- hand and hip
- generalized osteoarthritis- osteophytes of DIP and PIP (Heberden’s and Bouchard’s nodes)
9
Q
OA- primary, secondary?
A
- progressive deterioration!!
- primary- aging, idiopathic, genetic (nodal OA- DIP and PIP)
- secondary- disorders that damage joint surfaces
10
Q
OA subsets
A
- generalized
- nodal
- spondylosis
- erosive
- hyperostosis
- chondromalacia patella
11
Q
Generalized OA
A
-spine, hand, +other
12
Q
Nodal OA
A
-DIP and PIP (hereditary some)
13
Q
Spondylitis OA
A
-facet joint OA, frequently + DDD (degenerative joint dz)
14
Q
Erosive OA
A
-rare, DIP more common than PIP
15
Q
Hyperostosis OA
A
DISH (Diffuse Idiopathic Skeletal Hyperostosis)
- > 50 yo, M>F
- freq asx- cervical spine= dysphagia
- osteophytosis of spine- spans > 3-4 segments
- paraspinous ligaments= calcifications/ossification- “flowing wax” appearance on ant vertebral bodies
- preservation of disc space
- some assoc w DM
