O&G Flashcards

1
Q

How manage an OP head presentation

A

Likely will spontanoeusly rotate however if needs rotating after long labour ideally use kielland forceps

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2
Q

What is sign on examination of cocaine use causing placental abruption

A

Dilated pupils
Hyperreflexia

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3
Q

What give for hypermagnesaemia in after mag sulph

A

Calcium gluconate

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4
Q

How are ovarian masses managed

A

Assess on TVUSS whether any M features of cysts
If any M features then refer under 2WW
If
- under 50mm then can rescan in 3 months
- 50-70mm rescan in a years time
- over 70mm consider MRI or surgery

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5
Q

What do if premenopausal woman has an ovarian mass with any complex features of mass

A

Refer to gynae oncology and measure AFP, LDH and HCG

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6
Q

When refer for RFM

A

24 weeks

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7
Q

How long after a medical termination of pregnancy is pregnancy test expected to be positive

A

4 weeks- if longer suggests trophoblastic disease or retained products of conception

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8
Q

Causes of cervical tenderness

A

PID
Ectopic

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9
Q

What are sections to abortion act

A

2 doctors in good faith agree
A- continuing would risk life of pregnant woman
B- necessary to prevent grave physical or mental health risk of mother
C- pregnancy not exceeded 24 weeks and continuance would involve risk of injury to physical or mental health of mother
D- not exceedd 24 weeks and would involve risk to mental/physical health of existing children
E- born handicapped

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10
Q

Before 9+0 weeks what are options with regards to medical abortion options

A

Can do mifepristone and misoprostol at same time or with interval
- bleeding worse with together
- more likely to fail if together

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11
Q

Difference in prep for surgical abortion

A

All doxycycline 3 days, LMWH for 7 days and anti-D if Rh negative over 10 weeks
Before 14 weeks= oral misoprostol 1 hour before or sublingual misoprostol
14-19 weeks= osmotic dilators or vaginal misoprostol
19-23+6 weeks= osmotic dialtors and mifepristone both the day before

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12
Q

When is pregnancy test given post abortion

A

Medical up to 10+0 weeks
Is a multilevel pregnancy test which can measure HCG levels

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13
Q

Management of vaginal bleeding pre 6 weeks pregnant

A

Send home if no previous ectopic
Ask to do pregnancy test in 7 days
Return if positive or still bleeding or pain develops
If negative likely will have miscarried

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14
Q

What to do about anti-epileptics when breastfeeding

A

Any are fine except barbiturates

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15
Q

What type of C-section do if breech noticed whilst in labour

A

Category 2 C-section

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16
Q

What is regime for intrapartum antibiotics for GBS

A

Given at start then at 4 hourly intervals

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17
Q

When can COCP be started postnatally

A

3 weeks if not breastfeeding
6 weeks if are

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18
Q

How treat UTI if breastfeeding

A

Trimethoprin

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19
Q

What is combined test result for edwards

A

Low oestriol and HCG

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20
Q

If have been detected as having GBS in pregnancy what is management post natally

A

Stay in hospital for 24 hours to monitor

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21
Q

If woman comes in with menorrhagia, what may prompt to do hysteroscopy or TVUSS

A

Hysteroscopy
- persistent intermenstrual bleeding
TVUSS
- dysmenorrhoea
- bulky uterus

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22
Q

What is synctocinon vs synctometrine

A

Synctocinon= oxytocin
Synctometrine= synctocinon and ergometrine

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23
Q

What can iliac fossa pain with onset with exercise suggest

A

Ruptured ovarian cyst
Ovarian torsion

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24
Q

If has laparoscopy which is unremarkable but dye studies show blocked tubes, what is diagnosis

A

PID as endometriosis would appear on laparoscopy

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25
What is other name for balloon catheter used in PPH
Bakri catheter
26
When when going from Cu IUD to COCP what extra contraception needed
In first 5 days do not need condoms If any other times barriers for 7 days
27
When should ubilical hernias be referred
2 years
28
How assess viable intrauterine pregnancy on TVUSS
First assess if heartbeat If is not, see if foetal pole If there is measure CRL If not measure gestational sac
29
If have done USS and shown no heartbeat but is a foetal pole, how interpret CRL
TVUSS - Over 7mm then miscarriage likely so check with someone for viability or return in 7 days to rescan - If under 7mm repeat in 7 days Abdo USS - record CRL and repeat in 14 days
30
If no foetal pole how assess gestational sac
TVUSS - if over 25mm then check viability with someone or rescanin 7 days - if under repeat in 7 days Abdo USS - record length and repeat in 14 days
31
How is pseudosac excluded
Presence of eccentrically located hypoechoic structure with a double decidual sign
32
How to manage pregnancy of unknown location
Take HCG 48 hours apart If increase over 63% then intrauterine- USS in 7-14 days to confirm If greater than 50% decrease do pregnancy test in 2 weeks - return if positive If between 50 decrease and 63% increase come back in 24 hours for full review by early pregnancy
33
Management of threatened miscarriage
Tell them that if bleeding still there in 14 days return or gets worse return If disappears continue with antenatal care If history of miscarriage give vaginal progesterone until week 16
34
When do pregnancy test in medical miscarriage management
3 weeks If positive return if negative is complete
35
How does expectant management of ectopic work
Measure HCG at day 2, 4 and 7 Looking for fall of over 15% If after day 7 still decreasing repeat weekly If not a decrease of over 15% at any time then reassess
36
A 16-year-old girl attends accident and emergency complaining of mild vaginal spotting. Her serum beta hCG is 4016mIU/mL. She is complaining of severe left iliac fossa pain and stabbing sensations in her shoulder tip but are stable. Next investigation
TVUSS
37
Woman with twin pregnancy has really bad abdominal pain
Ruptured cyst
38
Management of bleeding post termination bleeding
If well do bloods to check if inflammatory response If unwell A-E and TVUSS to look for retained products of conception
39
What is the crown rump length
The distance between top of head to most inferior part/ bottom of their buttocks
40
What increases cardiac output in pregnancy
Increase HR Increase stroke volume
41
Acute presentation of sheehans syndrome
Headache and visual defect Agalactia
42
What is difference between anterior and posterior tongue tie
Both are due to short frenulums Can either be at the back or front If cant see frenulum then likely problem is posterior
43
Which NSAID give when breastfeeding
Ibuprofen
44
What do when depression a clear focus in menopause history
CBT
45
What is given intraoperatively in hysterectomy to precent infection
Co-amox
46
Management of nipple cracks
Advise to keep expressing milk but avoid feeding until heals
47
Management of vulvodynia
Paracetamol/ibuprofen Amitryptyline Gabapentin
48
Classification of prolapses
1- cervix 1cm above hymen 2- cervix between 1cm above and 1cm below hymen 3- cervix reaches introitus 4- cervix extends out of introitus
49
When are CTGs used in labour
High risk - DM - SGA Fever Meconium Synctocinon
50
Severe LIF pain with fever in post menopausal woman
Diverticulitis
51
Loin pain, tenderness and unwell in pregnant woman
Pyelonephritis- treat with cefalexin
52
Lung changes in pregnancy
Increased tidal volume Increased minute ventilation Gives feeling of breathlessness
53
Severe mittelschmerz presentation
Fever Abdo pain Fluid in pouch of douglas
54
If post subfertility screen, hormones, semen and STI screen negatove what do
If suspected underlying disease like endometriosis then laparoscopy and dye If unclear do hysterosalpingography
55
What is in foetal hydantoin syndrome
IUGR Hypoplastic nails Cleft lip/palate Microcephaly Limb problems
56
What are haematometra and haematocolpos
Blood in uterus and cervix respectively
57
Features of congenital syphilis
Blood stained rhinitis Hepatitis Meningitis Hitchinson teeth- small widely spaced teeth Saddle nose deformity Anterior bowing of shins Symmetrical knee swelling Perisoteal reactions
58
What are more common in a 20smt old cervical polyps or cancer
Polyps
59
How can BMI affect HRT administration method
If over 30 use dermal
60
What is risk of using nitrofurantoin near term
Neonatal haemolysis
61
Analogous male cells of granulosa and theca cells
Granulosa- sertoli Theca- leydig
62
How can atrophic vaginitis present
Urinary like stress incontinence Dyspareunia Vaginal bleeding
63
Where does ovarian pain get referred
Peri umbilical area
64
Medications which cause stress incontinece
Alpha blockers like doxazoxin
65
When during pregnancy do diabetics get their retinal screening
24-28 weeks
66
What is it when have irregular bleeding in first few years after menarche
ANNOVULATORY dysfunctional uterine bleeding
67
How often is ECV successful
60%
68
When consider third line options for shoulder dystocia
After 5 minutes
69
What does active management involve
Synctocinon after delivery of anterior shoulder EARLY clamping and cutting of cord, over 1 minute after delivery but less then 5 minutes Controlled cord traction after signs of placental separation DONE TO REDUCE PPH RISK
70
If has chosen an induction of labour with intrauterine death what does management depend on
If any bleeding, infection or ruptured membranes then c-section or induction For all other women offer induction, expectant or C-section If uterine scar with induction then must use mechanical options If no scar then use mifepristone then misoprostol
71
What prompts constant CTG usage
New onset bleeding Temp above 38 or suspected infection Oxytocin use Presence of meconium
72
If have given vaginal prostaglandin what do next
Reassess in 6 hours If bishops score under 7 give again
73
What type of drug is carboprost vs ergometrine
Carboprost- oxytocin analogue Ergometrine- alpha blocker
74
What analgesia used if epidural contraindicated
Remifentanil
75
In episiotomy what muscle are you trying to avoid
Ischiocavernous as involved in sexual function
76
When consider vaginal delivery in chord prolapse
Cervix fully dilated and head engaged Must use forceps
77
How are the anterior and posterior fontanelles described
Anterior- diamond Posterior- Y
78
What is Mazzanti technique
When pressure applied on abdomen to help with McRoberts
79
With SROM what is management
Sterile speculum exam or obtain a sample of liquor to test Offer IOL or expectant management until 24 hours
80
Shock out of proportion to bleeding and pain postnatally
Uterine inversion due to pulling on the round ligament which can cause vagal stimulation
81
MOA of nifedipine, atosiban and terbutaline
Nifedipine- CCB Atosiban- oxytocin antagonist Terbutaline- beta 2 agonist
82
Tests for PPROM
Alpha microglobulin-1 Insulin like globulin binding protein-1
83
What cervical length suggests preterm labour imminent
Under 15mm
84
What is cutoff fibronectin to indicate imminent labour
Over 50 suggests labour likely within 48 hours
85
Generally at what point should women be admitted when theyve started contracting
When cervix reaches 4cm dilated or contraactions every 5 minutes
86
How is vasa praevia best diagnosed
Trans vaginal and abdominal USS with colour doppler imaging
87
What is management of vasa praevia when identified pre rupture of membranes
Consider permanent hospitalisation from 32 weeks Give steroids from 32 weeks Aim for elective C-section 34-36 weeks
88
Dose of vitamin D in pregnancy
Should take 10mcg/day
89
Who should have an OGTT based on identification at booking
People with family history of DM Previous baby over 4.5kg BMI over 30 Ethnicity with high DM prevalence Previous GDM (has OGTT straight away)
90
Management of pre-existing DM
Ensure low BMI Good exercise and diet Folic acid until end of first trimester Stop all hypoglycaemics except insulin and metformin Screen for renal and retinal damage within first 3 months
91
If opt in for congenital syndrome screening what are options
If book early then offered between 11 and 13+6 weeks the COMBINED test Between 14+2 and 20+0 offered QUADRUPLE test
92
What do at 16 week visit
Discuss results of blood tests - infections - autoantibodies - rhesus D - Hb and folate etc Treat Hb Offer vaccinations - pertussis - influenza ideally in Oct-jan Discuss mid-pregnnacy scan
93
When are second blood taken in pregnancy
28 weeks
94
From when in pregnancy is anti-d required for miscarriage or PV bleeding
From 12 weeks for miscarriage
95
Post natal management of rhesus negative mothers
Cord blood taken and coombs test done Give anti-D
96
What are causes of high vs low AFP
High - NTD - pataus - gastro wall defects - multiple pregnancy Low - maternal DM - downs - edwards
97
When monitor TFTs if hypothyroid and pregnant
2 weeks after a dose change Once a trimester
98
Risks of using NSAIDs in pregnancy
PPHN Oligohydramnios Premature closure of DA
99
If metformin is not tolerated in GDM what use instead
Glibenclamide- sulphonylurea
100
What is association of phenytoin in pregnancy
Cleft lip
101
Best way of assessning EDD before and after 14 weeks
Before 14- crown rump length After 14- Biparietal diameter
102
If refuse induction of labour at 42 weeks what is needed
Twice weekly CTG and USS
103
Triple test for downs
High bHCG Low AFP Low oestriol
104
What is most appropriate method for monitoring SGA
Doppler of umbilical artery
105
If SFH is noted to be faltering, what is next thing do
USS to estimate foetal size
106
Management if epileptic has seizure during labour
IV lorazepam Second line IV phenytoin and tocolysis
107
What are indications to do an USS to estimate foetal size
SFH faltering SFH below 10th centile
108
Differentiating acute fatty liver and HELLP
Anaemia only in HELLP Hypoglycaemia in acute fatty liver
109
If pregnant or peuperal comes in with suspicion of DVT what do
LMWH and duplex USS
110
What do if pregnant or peuperal woman has come in with DVT suspicion and duplex USS negative despite high suspicion
Treat anyway and rescan on days 3 and 7
111
If pregnant or peuperal woman comes in with PE and DVT signs what do
ECG and CXR with treatment Duplex USS
112
If pregnant or peuperal woman has comes in with DVT and PE signs with positive duplex what do
No further investigations needed
113
If pregnant or peuperal woman has comes in with PE and no DVT signs what do
CTPA or V/Q
114
What can be used to treat polyhydramnios
Indomethacin
115
What is biggest risk factor for stillbirth
IUGR
116
If refuse insulin what offer
Glibenclamide
117
Management of candida
1 dose oral fluconazole then return if still bad Can use intravaginal or topical clotrimzole Fluconazole CI use itraconazole If aged 12-15 - refer to GUM - topical clotrimazole cream
118
Management of recurrent candida, BV and herpes
Candida- over 4x a year Induction and maintenance regime Induction- 3 doses of fluconazole, 1 every 3 days Maintenance- fluconazole once a week for 6 months BV- 4x a year Give metronidazole gel or refer to gum HSV-6 1st line- encourage bathing technique measures 2nd line- if fewer than 6 times a year can offer aciclovir for episodic treatment if over 6 can offer suppressive therapy every day
119
Which bacteria often colonises in BV
Gardnerella vaginalis Mycoplasma hominis
120
Management of persistent BV
Use alternative tx to one already used like if used pill use intravaginal
121
Management of HSV genitally
Ideally refer to GUM If refused give aciclovir
122
Management of ectopic if intrauterine pregnancy
Medical mx contraindicated
123
Management plan for uncomplicated chlamydia infection
1st line- encourage bathing technique measures 2nd line- if fewer than 6 times a year can offer aciclovir for episodic treatment if over 6 can offer suppressive therapy every day Test of cure 6/12 later
124
Dissemninated gonococcal disease presentation
Polyarthritis Vasculitic rash Fever
125
What is cobblestoned appearance of cervix seen in
Chlamydia
126
What is most likely cause of bartholins abscess
E coli
127
Chandelier sign
What is most likely cause of bartholins abscess
128
What becomes corpus luteum
Non-dominant follicles
129
How does ulipristal acetate work
Progesterone receptor modulator which inhibits ovulation
130
When need to double the dose of levonorgestel
BMI over 26 Weight over 70kg On liver induces such as carbamezapine and rifampicin
131
What do for contraception if take a teratogenic drug like sodium valproate
Use a highly efficient method like Cu-IUD, LNG-IUS or progestogen injection + Advise to use barrier protection OR If want to use other method like combined hormone contraception or progestogen MUST use barrier protection
132
What contraception avoid if unexplained vaginal bleeding
Intrauterine device and system Progestogen implant or injection
133
What do if miss 2 or more COCP
Take 2 on a day and discount other missed ones Use condoms until taken pills for 7 days If on week 1- consider emergency contraception if UPSI If week 2- no need for emergency contraception If week 3- finish the pack and then omit pill free period
134
If develop irregular bleeding on progesterone implant or injection what is management
Rule out other causes like STIs Then can initiate COCP
135
MOA of the different contraceptives
LNG-IUS= prevent proliferation of the endometrium and thicken cervical mucous Desogestrel= prevent ovulation Injectable and implantable= inhibits ovulation and thickens cervical mucous Older POP= thicken cervical mucous
136
How does DM, HTN and multiple CVD risk factors affect smoking
DM - any fine however if vascular disease then avoid combined If multiple - avoid injectable and combined HTN - controlled avoid combined and if uncontrolled avoid injectable too
137
What is placenta accreta vs increta
Accreta- through basal decidua into superficial myometrium Increta into myometrium
138
Management of asymptomatic placenta praevia at 32 weeks
Treat as outpatient - safety net about bleeding and sex Give steroids at 34-36 weeks Re-scan at 36 and deliver within a week if still placenta praevia
139
Management of someone with recurrent bleeding from low-lying placenta/placenta praevia
Tailor between hospitilisation and outpatient based on distance to hospital from home, transport, bleeding episodes and haem results Can admit steroids prior to 34 weeks Deliver 34-36 weeks
140
When and how should deliver if placenta praevia
If asymptomatic 36-37 weeks If bleeding and risks of preterm then 34-36+6 Ideally C-section but can consider vaginal if low lying and asymptomatic
141
Management of placenta accreta
MDT approach Planned c-section at 35-36+6 Trained memebers of team Blood products present
142
Resus for a minor PPH
A-E- assess for shock LIE flat IV access and take bloods for FBC, clotting Infused warmed crystalloid Obs every 15 mins
143
Fluids used for major PPH
2L isotonic crystalloid then 1.5L colloid
144
How is PPH prevented
If no risks and vaginal - oxytocin IM 10units If risks - ergometrine-oxytocin unless HTN If c-section - oxytocin slow infusion
145
When do you transfuse platelets in PPH
If below 75
146
Management of suspected endometritis
Admit to hospital High vaginal and endocevical swabs IV clindamycin and gentamicin
147
What drugs should be avoided if breastfeeding
Abx- Tetracyclines, chloramphenicol, sulphonamides Lithium Benzos Aspirin Carbimazole Sulphonylureas Amiodarone Chemo
148
What happens if rhesus positive baby born to negative mother
500IU within 72 hours Kleihauer test
149
Cerebral venous thrombosis presentation, investigation and management
Severe headache but can get blurred vision MRI IV heparin
150
Who is at high risk for pre-eclampsia and needs aspirin from week 12 of pregnancy
If 1 of - HTN during previous pregnancy - CKD - DM - autoimmune condition If 2 of - family history of pre-eclampsia - 10 year gap between pregnancy - multiple pregnancy - over 40 - BMI over 35
151
Chronic HTN management in pregnancy
Stop thiazides, ARB and ACEi Continue old treatment unless under 70/110 If over 90/140 start labetalol CI use nifedipine Both CI use methyldopa Give aspirin from week 12 and offer PIGF past week 20 to check for pre-eclampsia Measure every 2-4 weeks
152
Postnatal mangement if someone with chronic HTN or gestational HTN has given birth
Measure BP daily for first 2 days Once between 3-5 days Keep below 140/90
153
Management of gestational HTN
If 140/90-159/109 then refer to be seen within 24 hours by obstetrician- use pharmacological agents to reduce below 135/85 If over 160/110 then admit immediately and treat until below 160/110- measuring every 15-30 mins
154
How are people with gestational HTN monitored
Weekly - BP -Urine dip - FBC, LFT and renal function Every 2 weeks - USS
155
Who should be offered placental growth factor
Everyone with gestational HTN or chronic HTN post 20 weeks If low indicates high risk of eclampsia
156
How can risk prediction in pre-eclampsia be assessed
PREP-S prediction model
157
If pre-eclampsia how are you monitored
If treated as outpatient for mild pre-eclampsia - BP every 48 hours - FBC, LFTs, renal function 2x a week - fetal USS every 2 weeks If in patient for severe - FBC, LFTs, renal function 3x a week
158
Management plan for premature labour
Determine if rupture of membranes If no rupture just dilation and contractions - admit for tocolytics and steroids (in case goes into labour) If rupture - admit - steroids if before 34 weeks - mag-sulphate if before 30 - erythomycin until delivery/10 days - contact neonatologist
159
What do with delivery in pre-eclampsia
If before 36 weeks continue with surveillance and consider antenatal steroids unless - sats less than 90 - failure to control BP with 3 anti-hypertensives - placental abruption - continuining deterioration of symptoms and blood results If after 36+6 then deliver within 48 hours
160
What do if no fetal movements felt by 24 weeks
Referral to foetal medicine unit
161
Causes of oligohydramnios
Premature rupture of membranes IUGR Post-term gestation Pre-eclampsia Potter sequence Posterior urethral valve
162
Who is regular US surveillance to measure cervical length indicated in
History of preterm birth or spontaneous loss in second trimester but cervical length over 25mm If found to go under 25mm pre 24 weeks then do TV cerclage
163
Who is vaginal progesterone indicated in for prevention of preterm birth
History of spontaneous preterm birth or miscarriage in second trimester
164
How should ICP be monitored
1 week after initial blood tests then on individual basis
165
When give birth with ICP
Depends on levels of bile acids If 19-39: by 40 weeks If 39-100: 38-39 Over 100: 35-36
166
If have asymmetrical IUGR how are monitored
USS every 2 weeks Doppler USS twice weekly
167
If develop chorioamnionitis after PPROM how manage labour
Induce in 24 hours
168
Antibiotic choice if allergic to penicillin in GBS IAP
If non-severe allergy use a cephalosporin If severe use vancomycin
169
What do if prelabour rupture of membranes and GBS status is positive
Before 34 weeks expectant management After 34 weeks can expedite delivery If after 37 immediate induction
170
Management of herpes infection in pregnancy
In first and second trimester - treat with oral acyclovir unless encephalitis - for delivery treat from 36 weeks with aciclovir until delivery If in third trimester - aciclovir until delivery and should be C-section
171
How is parvovirus confirmed in pregnancy then what is management
2 positive IGM readings Infection takes 6 weeks to affect baby Therefore referral to foetal medicine within 4 weeks to do an USS of the middle cerebral artery every 2 weeks
172
Management of UTI in pregnancy first 2 trimesters
First line- nitrofurantoin for 7 days Second line (no response in 48 hours or contraindicated)- cephalexin, amoxicillin
173
How manage refusing a c-section with HSV
IV infusion of aciclovir during the pregnancy and close liason with neonatologist
174
In HIV vaginal delivery, what is not recommended
Prolonged rupture of membranes Artificial rupture of membranes
175
What suggests foetal anaemia on middle cerebral artery USS
Elevated peak systolic velocity
176
Management of chickenpox if breastfeeding
Aciclovir within 24 hours of onset of rash
177
Are IAP given for GBS if C-section
No unless rupture of membrane or preterm
178
What antibiotics if get PID in pregnancy
IV erythomycin and ceftriaxone
179
Management if varicella infection around the time of birth
Try to give birth at least 7 days after onset of rash If give birth within 7 days then give baby VZIG If in 7 days post natal then give infant VZIG
180
In HIV vaginal delivery, what is not recommended
Prolonged rupture of membranes Artificial rupture of membranes
181
Hepatitis B vaccine schedule if born to positive mother
One within 12 hours of birth One at 1-2 months One at 6 months
182
Management of feto-foetal transfusion syndrome
Refer to feotal meicine for ablation of interconnecting vessels
183
When are twins recommended to be born
Dichorioic diamniotic- 37 Monochorionic diamniotic- 36 Monochorionic monoamniotic- 32-33+6
184
What causes pansystolic murmur in pregnancy
Dilation of tricuspid valve
185
Which conditions reduce in severity over pregnancy
MS and rheumatoid arthritis
186
What needs to be done to AEDs during pregnancy
Increase the dose
187
How does pruritic urticarial papules and plaques of pregnancy present
Itchy rash starting on stretch marks and spreading anywhere with umbilical sparing Starts at end of pregnancy
188
How does pemphigoid gestationis present
Itchy rash which starts in the umbilicus that can develop into blisters
189
How does prurigo gestationis present
Rash of the trunk and arms with abdominal sparing
190
How does impetigo herpetiformis present
Blistering skin condition with cocontaminat febrile illness
191
Postnatal management of pre-eclampsia
If over 160/100 then have to stay in If over 150/100 then must be monitored every 2 days If less than 150/100 checked weekly and weaned off anti-hypertensives If less 130/80 can stop anti-hypertensives
192
Post natal management of GDM
If new onset GDM- stop all medications after birth, offer fasting glucose 6 weeks after If T1DM- put on sliding scale and when starts eating again give pre-pregnancy dose If T2DM- can resume metformin but avoid others
193
At 6 weeks postnatal how interpret fasting glucose
If under 6- repeat annually If 6-6.9- At high risk of developing DM so offer lifestyle interventions Over 7- initiate testing for T2DM
194
What drugs can use for vasomotor symptoms in menopause that are not HRT
SSRI- fluoxetine, citalopram SNRI- venlafaxine Clonidine (alpha 2 agonist) Gabapentine
195
Genitourinary symptoms management in menopause
1st -Vaginal oestrogen 2nd- increase dose 3rd- opsemifene
196
Contraindications to HRT
Breast cancer currently or in past Undiagnosed vaginal bleeding Untreated endometrial hyperplasia Active liver disease Thrombophilic Previous VTE Oestrogen dependant cancer history
197
Can you have HRT with prior VTE
Only if being actively anti-coagulated
198
Management of premenstrual syndrome
Mild - lifestyle- exercise, small meals 2-3 hours apart, stop smoking alcohol Moderate - COCP Severe - SSRI for luteal phase or continuous
199
What are at risk adolescents for PCOS
Girls who do not quite meet the criteria for PCOS diagnosis
200
How manage at risk girls for PCOS
Start on the COCP then before 8 years post menarche withdraw the COCP for 3 months and assess if is hyperandrogenin anovulation
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Then need to assess endometrial thickness in PCOS
If less than 1 period every 3 months
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Amenorrhoea management in PCOS
prescribe cyclical progestogen for 14 days to induce a withdrawal bleed and then refer for TVUSS If over 10mm get sampling If normal then offer either low dose COC, cyclical progestogen or LNG-IUS depending on whether wants withdrawal bleeds or has acne etc If does not wish to have any of these then refer to specialist where will be offered USS every 6-12 months Weight loss also useful
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Management of pain in primary dysmenorrhoea
Mefanemic acid and paracetamol 2nd line COCP 3rd line can use POP or Mirena
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What are spiral arteries
Supply the endometrium
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Investigations for primary amenorrhoea
TSH FSH/LH Prolactin Testosterone TVUSS
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What do if prolactin 500-1000 Primary amenorrhoea investigation
Repeat
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How to manage amenorrhoea caused by excess exercise, weight loss or stress
Refer all to endocrinologist to rule out pituitary tumour If ruled out Excess exercise- reduce exercise and refer to sports physician if possible Stress- manage stress Weight loss- dietician or relevant services if ED
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When refer to gynae for secondary amenorrhoea
POI in under 40 Recent uterine or cervical surgery suggesting asherman or endometritis Infertility
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How to daignose asherman syndrome
Hysteroscopy
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Management of vulvovaginitis
Good hygiene Wear cotton undergarments
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Management plan if unprovoked vulvodynia
First line- amitryptylline Second line- gabapentin or pregabalin
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What type of drug is mefanemic acid
Prostaglandin inhibitors
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In PMS, how give the COCP
Omit pill free period
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What defines primary dysmenorrhoea
It occurs within 1 year of menache
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What is best drug for dysmenorrhoea if dont want to take a pill every day
Mefanemic acid as can be given as a short course
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How to interpret mid luteal progesterone
Under 16- repeat and refer if chronically low 16-30- repeat Over 30- normal indicating ovulation
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Which contraceptives cause infertility after removal
Injectable- a year Dermal and vaginal ring a few months
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Management of mild and moderate OHSS
As an outpatient - paracetamol - oral fluids - monitor every 2-3 days - can do paracentesis if need to in outpt setting with USS
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When admit with OHSS
- are unable to achieve satisfactory pain control - are unable to maintain adequate fluid intake due to nausea - show signs of worsening OHSS despite outpatient intervention - are unable to attend for regular outpatient follow-up - have critical OHSS
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Normal ranges for male sperm factors
Motility- at least 50% should have normal motility Morphology- over 4% good morphology Sperm count- over 15 million is good sperm count Volume- over 1.5 ml
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How does clomiphene regime work
In oligomenorrheic women give a progestogen for 10 days and anticipate a withdrawal bleed. Once this happens give clomiphene on day 2 of the period and continue for 5 days It is most effective when patient on period
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How manage infertility in PCOS in GP
If BMI over 25 recommend weight loss Ask to have regular sex for 2 years then can refer to fertility clinic for clomiphene etc
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What does dyskaryosis mean
Hyperchromatic nucleus or irregular nuclear chromatin
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How is normocytic anaemia managed in pregnancy
Trial of oral iron for 2 weeks If no improvement then further tests
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When do multiple pregnancy women have blood tested
Booking and 28 weeks On top of this have at 20-24
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What causes severe suprapubic pain post operation
Urinary retention
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Leading maternal cause of death
Suicide
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How are contractions assessed on CTG
Less than 5 in 10 minutes= white 5 or more in 10 minutes, hypertonus = amber
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How is baseline foetal HR determined
Looking at mean foetal HR over last 10 minutes
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How is foetal HR assessed on CTG
White- baseline between 110-160 Amber- 100-109, can't determine base line or increase of HR over 20 since start of labour or review 1 hour ago
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How deal with HR 100-109 but has been stable throughout whole labour with normal accelerations and decelerations
Manage as normal labour
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How is variability of CTG assessed
Measure the difference in HR between highest and lowest HR in a minute segment in between contractions
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How manage an absence of variability
Low threshold for expediting
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How assess variability on a CTG
White- 5-25 beats per minute Amber- fewer than 5 BPM for 30-50 minutes, more than 25 for up to 10 minutes Red- fewer than 5 BPM for more than 50 minutes, more than 25 beats per minute for 10 minutes, sinusoidal pattern
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When need to get an urgent review by obstetrician for consiering expediting delivery when reduction in variability of under 5 minutes
- combined with intrapartum rfx - combined with rise in foetal HR
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What are decelerations defeined as
Reduction in foetal HR by over 15 lasting at least 15 seconds
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What defines repetitve decelerations
If occur in over 50% of contractions
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How are decelerations classified
White- No decelerations, early decelerations, variable decelerations Amber decelerations- repetitive variable decelerations with any concerning characteristics for less than 30 minutes, variable decelerations with any concerning characteristics for more than 30 minutes, repetitive late decelerations for less than 30 minutes Red- repetitive variable decelerations with any concerning characteristics for more than 30 minutes, repetitive late decelerations for more than 30 minutes, acute bradycardia, or a single prolonged deceleration lasting 3 minutes or more
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What are early vs late decelerations
Early= slowing with onset early in contraction and returns to baseline by end of contraction Late= slowing after onset of contraction and low point more than 20 seconds after peak of contraction
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What is hypertonus
Contraction lasting over 2 minutes
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What are accelerations defined as
Increase in HR over 15 lasting over 15s
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How deal with accelerations on CTGs
Sign of normal and healthy baby, no concern
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What makes a CTG suspicious vs pathological
Suspicious= 1 amber feature Pathological= 1 red or 2 amber
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Neonatal care of baby
APGAR at 1 and 5 minutes Record time of first respiration Ensure skin to skin ASAP Dry and wrap in a towel Initiate feeding within I hour After 1 hour measure head circumfrence ,weighing and bathing
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Care of babies in presence of meconeum
Assess HR, tone and RR If abnormal use laryngoscope to remove meconeum If healthy admit to neonatal ward with observations at 1,2,4,6,8,10,12 hours
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Management of baby born after prelabour rupture of membranes 24 hours pre labour
Keep baby in for 12 hours Assess at 1, 2, 6 and 12 hours
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Varicella exposure in 7 days post partum
Give VZIG only if mum not immune