nutritional malabsorption Flashcards
what diseases are associated with Mal-digestion?
- chronic pancreatitis
- cystic fibrosis
- pancreatic carcinoma
what diseases are associated with inadequate absorptive surface?
- intestinal resection
- gasto colic fistula
- jejunoileal bypass
what diseases are associated with bile salt deficiency?
- cirrhosis
- cholestasis
- bacterial overgrowth
- impaired ileal reabsorption
- bile salt binders
what diseases are associated with lymphatic obstruction?
- lymphoma
- Whipple’s disease
- intestinal lymphagiectasia
what diseases are associated with vascular disease?
- constructive pericarditis
- right sided heart failure
- mesenteric arterial/venous insufficiency
what diseases are associated with mucosal disease?
- infection (giardia, whiles disease, tropical sprue, inflammatory diseases, radiation enteritis, eosinophilic enteritis, ulcerative jejunitis)
how is energy balanced during disease?
in absence of food, glucose is maintained through mobilisation of stores of glycogen and if prolonged gluconeogenesis, lipolysis
what happens when energy is balanced during disease?
- cytokines
- TNF alpha insulin resistance, glycolysis
- IL2 glucose metabolism
- IL4 lipid and glucose metabolism
- IL6 lipolysis
- activity and appetite reduced
what are the risk factors for refeeding syndrome?
- BMI less than 16 kg/m^2
- unintentional weight loss greater than 15% within the last 3-6 months
- little or no nutritional intake for more than 10 days
- low levels of potassium, phosphate or magnesium prior to feeding
what are the key characteristics of the chronic illnesses?
- start with food
- may have long term internal feeding
- focus on balanced diet
- diet to increase energy intake
- diet to manage blood glucose
- diet to reduce workload of kidney
- diet to reduce inflammation
- diet to support treatment
what are the key characteristics of acute illnesses?
- start with food
- consider other routes such as enteral/parenteral
- diet to meet energy demand and reduce catabolism
- diet to support recovery - micronutrients and macronutrients