nutritional malabsorption Flashcards

1
Q

what diseases are associated with Mal-digestion?

A
  • chronic pancreatitis
  • cystic fibrosis
  • pancreatic carcinoma
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2
Q

what diseases are associated with inadequate absorptive surface?

A
  • intestinal resection
  • gasto colic fistula
  • jejunoileal bypass
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3
Q

what diseases are associated with bile salt deficiency?

A
  • cirrhosis
  • cholestasis
  • bacterial overgrowth
  • impaired ileal reabsorption
  • bile salt binders
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4
Q

what diseases are associated with lymphatic obstruction?

A
  • lymphoma
  • Whipple’s disease
  • intestinal lymphagiectasia
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5
Q

what diseases are associated with vascular disease?

A
  • constructive pericarditis
  • right sided heart failure
  • mesenteric arterial/venous insufficiency
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6
Q

what diseases are associated with mucosal disease?

A
  • infection (giardia, whiles disease, tropical sprue, inflammatory diseases, radiation enteritis, eosinophilic enteritis, ulcerative jejunitis)
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7
Q

how is energy balanced during disease?

A

in absence of food, glucose is maintained through mobilisation of stores of glycogen and if prolonged gluconeogenesis, lipolysis

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8
Q

what happens when energy is balanced during disease?

A
  • cytokines
  • TNF alpha insulin resistance, glycolysis
  • IL2 glucose metabolism
  • IL4 lipid and glucose metabolism
  • IL6 lipolysis
  • activity and appetite reduced
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9
Q

what are the risk factors for refeeding syndrome?

A
  • BMI less than 16 kg/m^2
  • unintentional weight loss greater than 15% within the last 3-6 months
  • little or no nutritional intake for more than 10 days
  • low levels of potassium, phosphate or magnesium prior to feeding
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10
Q

what are the key characteristics of the chronic illnesses?

A
  • start with food
  • may have long term internal feeding
  • focus on balanced diet
  • diet to increase energy intake
  • diet to manage blood glucose
  • diet to reduce workload of kidney
  • diet to reduce inflammation
  • diet to support treatment
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11
Q

what are the key characteristics of acute illnesses?

A
  • start with food
  • consider other routes such as enteral/parenteral
  • diet to meet energy demand and reduce catabolism
  • diet to support recovery - micronutrients and macronutrients
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