Nutritional Assessment - Iron, Dietary, Clinical, Functional Flashcards
Name the progression of IDA
- Decreased stores
- Iron transport increases
- Degradation of iron
Decreased iron stores is reflected in what lab value?
Serum ferritin <20 ug/L
Increased iron transport is reflected in what 2 lab values?
Transferrin saturation decreases (<30%)
Total Iron Binding Capacity increases (TIBC) (>4.5 mg/L)
Why does TIBC increase?
Because transferring saturation decreases, more possibility for iron to bind
How to calculate transferrin saturation?
Serum Iron / TIBC x 100
<30% signals a deficit
Free erythrocyte protoporphoryin increase/decrease during IDA?
Increase, since iron will leave heme group to join circulation and will be replaced by zinc. Protoporphoryin is the transport protein of zinc
What decreases in the progression of Fe deficiency?
- Iron stores
- Serum ferritin
What remains unchanged in the progression of Fe deficiency?
- RBC iron
- Transferrin saturation
- Free erythrocyte protoporphoryin
- Hemoglobin concentration
What immediately decreases when Fe deficiency progresses into IDA?
Hemoglobin concentration
What will start to decrease when Fe deficiency progresses into IDA? What will increase?
- Transferrin saturation decreases
- TIBC increases
- Free erythrocyte protoporphoryin increase
What stays constant at a low level when Fe deficiency progresses into IDA?
-Serum ferritin
What is the final indicator of IDA?
Decreased RBC iron
IDA is usually identified off of what lab result?
Hemoglobin concentration <120 g/L for women and <140 g/L for men
Serum iron reflects ___ and is low in the ____ deficient state
the iron bound to transferrin, EARLY (transferrin increases, saturation decreases, TIBC increases)
What is indicative of a progressing deficiency state of folate deficiency? Later state?
- Serum folate
- RBC folate
Lab results indicate megablastic and macrocytic RBCs and an increase in methylmalonic acid, this is indicative of what anemia?
B12
Lab results indicate megablastic and macrocytic RBCs and an increase in homocysteine, this is indicative of what anemia?
Most likely Folate and B12
Folate deficiency can be suspected when RBCs are megoblastic and macrocytic. What lab results would confirm this?
-Low serum folate and RBC folate BUT normal B12 levels
What lab value would indicate B12 deficiency but NOT folate if RBCs are megoblastic and macrocytic?
High amounts of methylmalonic acid
What lab value may decrease in the progression of deficiency of B12? What would confirm B12 deficient anemia?
Low serum B12
Increased Methylmalonic acid
Iron requirements are increased at what stage of life?
Pre-menopausal women
Pregnant women
What are excellent sources of iron?
> 3.5 mg
What are good sources of iron?
> 2.1 mg
What are sources of iron?
> 0.7 mg
Give examples of excellent heme sources of iron
- clams
- oyster
- liver
Give examples of good heme sources of iron
- cooked beef
- blood pudding
- dark turkey
Give examples of heme sources of iron
- chicken, veal, ham, pork
- fish
- shrimp
Give examples of excellent non-heme sources of iron
- Cooked legumes
- Pumpkin seeds
- Fortified cereals
- Tofu
Give examples of good non-heme sources of iron
- Canned legumes
- enriched egg noodles
- dried apricots
Give examples of non-heme sources of iron
- Nuts
- Sunflower seeds
- Breads
- Cooked oatmeal
- Wheat germ
Name some risk factors for poor iron status
- Diet low in heme-iron, vitamin C and fortified foods
- Diet high in tannins & polyphenols found in coffee and tea
- Diet high in phytates and oxalates, found in beets and spinach
- Regular aspirin use (GI bleeding)
- Mennorhagia
- > 3 annual blood donations
- > 3 pregnancies
More that ___ risk factor is grounds for investigating IDA
1
Iron supplementation is recommended when __
IDA diagnosed or pregnancy