Management of Obesity Flashcards
What are the 5 As of obesity management?
ASK for permission ASSESS obesity risks/causes ADVISE on health risks/treatment AGREE health outcomes, behaviour goals ASSITS in accessing resources
There are health benefits associated with ____ weight loss
5-10%
What are the therapeutic objectives in weight loss?
- Changes in eating behaviours
- Weight-loss/stabilization
- Prevention of weight re-gain
- Reduction in risk factors
Name some improvement in diabetes control with weight loss
- Increased glucose tolerance
- Increase insulin sensitivity
- Decreased medication
Name some improvement in cardiovascular health with weight loss
- Normalize TG levels
- Increase HDL, decrease LDL
- Improve CHD risk profile
- Decreased medication
Name some improvement in hypertension with weight loss
- Decreases systolic BP, blood volume, cardiac output
- Decreased sympathetic activity
- Decreased need for anti-hypertensive medication
Benefits of a 10 kg weight loss in mortality?
-Decrease total mortality, diabetes deaths, obesity related cancers
Benefits of a 10 kg weight loss in BP?
Decrease 10 mmHg systolic
Decrease 20 mmHg diastolic
Benefits of a 10 kg weight loss in angina?
91% decrease in symptoms
33% increase in exercise tolerance
Benefits of a 10 kg weight loss in lipids?
Decrease total cholesterol, LDL cholesterol, TGs
-8% increase in HDL
Benefits of a 10 kg weight loss in diabetes?
> 50% reduction in developing diabetes
30-50% decrease in fasting blood glucose
Decrease HmgA1C
Main difference between weight loss and weight maintenance diets?
Weight loss = hypocaloric
Weight maintenance = isocaloric
What is in common between weight loss and weight maintenance diets?
- Adequate nutrients
- Behavioural modification
- Physical acitivities
What is to consider about the isocaloric diet ?
Will be adjusted the the persons CURRENT weight, after the weight-loss, and therefore may be similar or the same amount of calories as the hypocaloric diet
How do we determine an appropriate energy intake for weight loss in obese patients?
1) Calculate TEE (with IOM or MFSJ)
2) Subtract 500 kcal
500 kcal will lead to a 1 lb or 0.5 kg loss per week. Explain the principle behind this
One pound is equal to 454 g of adipose tissues, where 87% of adipose tissue is fat.
0.87 x 454 g = 395 g of fat
395 g x 9kcal/g = 3500 kcal
3500 kcal/7 days= 500 kcal/day to induce 1 lb weight loss in one week
What is important to consider when adjusting for an energy deficit?
We want to induce an hypo-caloric diet that has a large enough energy deficit to induce weight loss without inducing the physiological adaptations to starvation (under hormonal/hedonic control)
In obese patients, we should aim for a modest weight loss of ___
5-10% of CBW
How could we estimate target weight?
Use simple quick method (if we know kcal, and if we know total calories with deficit, we can know the weight)
How could we recommend weight loss?
Using stepwise approach (loss–>stabalize –> loss)
What will the stepwise approach allow?
Allow the patient to adjust to behavioural modifications, readjust energy expenditure and energy metabolism.
Pro, CHO, Fat and vitamin supplementation on severely low energy diets ? (<600kcal/day)?
Pro: 1.5 g/kg/day
CHO: >50 g/day (prevent ketosis)
Fat: 3.6 g/day linoeic acid
Vit Supplements: Yes
Pro, CHO, Fat and vitamin supplementation on very low energy diets ? (600-1200 kcal/day)?
Pro: 1.1-1.2 g/kg/day
CHO: 45-65% (normal)
Fat: <30% (normal)
Vit Supplements: yes
Pro, CHO, Fat and vitamin supplementation on low energy diets ? (1200-1500 kcal/day)?
Pro: 1.0-1.2 g/kg/day
CHO: 45-65% (normal)
Fat: <30% (normal)
Vit Supplements: Optional, but recommended
Diets at and below ____ is difficult to reach nutrient requirements
1500 kcal
What are the priorities in dietary intervention for people with obeity? (CAPP)
- Creating and energy deficit
- Avoid nutritional deficiencies
- Preserve lean mass
- Promote long-term adherence
In weight management for obesity we want to __
Change behavioural and dietary habits for life
What were some key results in high protein diets for weight-loss (study)
- REDUCTION in body weight, fat mass and serum TGs
- LESS reduction in fat-free mass (LBM)
- NO CHANGE in cholesterol, fasting glucose, BP, insulin
In the high-protein diet for weight-loss, there was less reduction if fat-free mass - what does this mean?
That the diet spared endogenous protein breakdown, meaning that the individual will not experience a decrease in REE which will facilitate weight-loss
What where the 4 diets tested after individuals followed the very low cal diet for 8 weeks?
High protein high glycemic
High protein low glycemic
Low protein low glycemic
Low protein high glycemic
Which diet resulted in the greatest weight-regain vs control?
LPHG>LPLG>HPHG?HPLG
Which diet resulted in virtually NO weight-regain?
High protein, low glycemic diet
Low protein =
13% AMDR
High protein =
25% AMDR
High protein and low glycemic diets also experienced what?
Lower dropout, no changes in satiety, less weight regain. More realistic to follow, and protein was not unrealistically high (22-25%)
What is the criteria to register at the National Weight Registry?
Lost more than 30 lbs and have kept off for >1 year
How did 89% of National Weight Registrants succeed?
Through diet and physical activity modifications
What are the common factors of successful registrants of the National Weight Registry?
- Low-energy, low-fat w/ little varied diets
- Exercise 90% 1 hour/day
- Less than 10hrs/week of TV
- Eat breakfast
- Self-weight and monitor weight
What are the two KEY messages in management of obesity?
- A modest weight loss of 5-10% is beneficial
- Weight-maintenance and weight loss should be long-term/life-long goals
Protein AMDR
10-35%
Protein AMDR for weight-loss
25-30%
Protein AMDR for weight-maintenance
15-20%
CHO AMDR
45-65%
CHO AMDR for weight-loss
45-65% (UNLESS on severely restricted energy diet)
CHO AMDR for weight-maintenance
45-45%
CHO recommendation for weight-loss/maintenance?
High fibre, low GI, whole grain CHOs
Fat AMDR
20-35%
Fat AMDR weight-loss & maintenance
<30%, enough essential FA, low trans/saturated fats
Name some stats about PA
- 50% Canadians inactive
- More females than males inactive
- PA decreases with age
Active adults have ____ decreased risk of premature mortality
20-35%
What is encouraging about PA for sedentary individuals?
A modest increase in PA has been associated with LAGE improvements in health status, especially in risk of mortality (taper off as aerobic fitness increases - more significant in men)
Which diseases drastically decrease in risk, then stabilize as PA increases (curvi-linear relationship?) CODS
- CHD
- Osteoporosis
- Diabetes
- Stroke
What linearly decreases as activity increases?
Weight gain
What increases as physical activity increases?
Muscoskeletal injury
In someone who is usually sedentary, what is an encouraging message about disease risk and PA?
A small increase in PA can have large health benefits in reducing risks of diseases (CODS) and weight gain
PA and E to prevent weight gain? Preventative of what % of weight gain?
PA: 150-250 min/week
E: 1200-2000 kcal/day
Prevent weight gain of greater than 3% in most adults
PA for minimal weight loss?
<150 mins/week
PA for moderate weight loss?
> 150 mins/week
PA for greater weight loss? Approx how many kg?
> 225-420 mins/week
~5-7.5 kg of weight loss
PA for weight maintenance?
~200-300 kcal
“more is better?”
What is lifestyle PA protective of?
May counter the small energy balances found in obese adults
What is the paradox in increases PA and energy restiction
If the energy restriction is too severe, it will hinder weight loss. (
Does resistance training support weight loss? How about with diet restriction?
NO for either
What may resistance training improve?
Chronic disease risk factors, osteoporosis
If used, pharmacological treatments must not be ___
the sole treatment and MUST be used i conjunction with dietary, activity and behavioural modifications
What is orlistat?
lipase inhibitor
Describe the mechanism of action of orlistat (lipase inhibitor)
Acts in the GI (must be take with food), and acts as a non-absorbed inhibitor of lipase which produces a malabsorption of 30% of fat, and will become excreted.
What are the results of using orlistat?
~50% effective individuals, resulting in a 4kg weight loss and improved co-morbidities
What side-effects are associated with orlistat?
AFFECT DAILY LIVING ACTIVITIES
- fecal and urinary urgency
- fatty stool
- Vit ADEK deficiencies
What is the mechanism of action for appetite suppressants?
Acts on the CNS in the central regulation area of appetite to decrease appetite and increase satiety.
What are appetite suppressants?
- Seretonin agonist (seretonin = anorexigenic)
- Amphetamine inhibitor
What are risks associated with appetite suppresants?
- May cause addiction, nausea, dizziness, CVD ris
What are the 3 factors of readiness assessment? (BPE)
- Behavioural
- Pyschological
- Environmental
What are some behavioural aspects of RA?
- Ability to increase PA
- Success of previous weight loss
- Self-control
What are some psychological aspects of RA?
- Attitudes about weight loss
- Confidence in ability to lose weight
What are some environmental aspects of RA?
- Social support
- Life circumstance
Selection criteria for weight management program is based on what? CFN
- Composition
- Food plans
- Nutrition counselling
What is intricately related in management of obesity? How is it sustained?
Diet, physical activity and behavioural modifications
Sustained by maintenance.
Overall, what are some key recommendations you would make to a person living with obesity?
- Assess readiness to change, state-of-change model ..
- Diet high in protein (25-30%), <30% fat, normal range of carbohydrates that are low GI
- Increase physical activity (pedometer, walking, low amounts of effort - increase lifestyle PA)
- NO starvation/extremely low kcal diets, fad diets etc.