Nutrition & Blood Flashcards
Therapeutic Hormones
Drugs for treatment of bone and calcium homeostasis
Calcitonin
MoA:
Inhibits mobilisation of calcium from bones
Indication:
Osteoporosis, hypercalcaemia
Adverse Effects/Interactions:
Abdominal pain
Antacids
Bisphosphonates
Drugs for treatment of bone and calcium homeostasis
Alendronate, Pamidronate
MoA:
Inhibits osteoclast function and bone resorption
Indication:
Osteoporosis, hypercalcaemia
Adverse Effects/Interactions:
Drugs for hypocalcaemia
Drugs for treatment of bone and calcium homeostasis
IV calcium gluconate,
vitamin D, Parathyroid Hormone
MoA:
Restoration of calcium levels and metabolism
Indication:
Hypocalcaemia, bone loss
Adverse Effects/Interactions:
Vitamin D deficiency
Drugs for treatment of bone and calcium homeostasis
vitamin D (colecalciferol, calcitriol (1,25-dihydroxyvitamin D)
MoA:
Restoration of vitamin D levels
Indication:
Vitamin D deficiency
Adverse Effects/Interactions:
Selective estrogen receptor modulator (SERM) (for osteoporosis)
(Drugs for treatment of bone and calcium homeostasis)
Raloxifene
MoA:
Stimulation of oestrogen function in bone
Indication:
Prevention of bone fractures
Adverse Effects/Interactions:
Hot flushes
Warfarin
Monoclonal antibody
Drugs for treatment of bone and calcium homeostasis
Denusomab
MoA:
Inhibition of osteoclast function and bone resorption
Indication:
Osteoporosis
Adverse Effects/Interactions:
Hypocalcaemia
Oral Iron Compound
Drugs for treating anaemia
Ferrous Sulphate
MoA:
Iron provision
Indication:
Iron-deficient anaemia
Adverse Effects/Interactions:
Constipation, Antacids
Water Soluble Vitamin: Folic Acid
Drugs for treating anaemia
Folic Acid
MoA:
Supports nucleic acid synthesis
Indication:
Folate-deficient anaemia
Adverse Effects/Interactions:
Water Soluble Vitamin: B12
Drugs for treating anaemia
Vitamin B12 (parenteral)
MoA:
Enzyme co-factor
Indication:
Pernicious anaemia
Adverse Effects/Interactions:
