Nutrition

Question 1

Answer 1

Question 2

Answer 2

Objective: compare measurement of biochemical analytes before and after feedign on 100 healthy dogs >15kg.
Intervention: food witheld for 10-26hrs, then fed 2/3 their RER, assessed reported allowable total error (TEa) for analytes
Results: Dogs with at least one meaurement >TEa = 92% for triglycerides, 66% for BUN, 46% for phos, 17% for glucose, 9% bilirubin 5% SDMA, 2% creatinine, and 0% for cholesterol and albumin. Post prandial lipase never exceeded RI in dogs with normal fasted lipase
Conclusion: Witholding food is generally not necessary before routine biochemistry in healthy dogs. Might help to limit variablity in triglycerides and phosphorus.

Question 3

Post prandial sampling does not imact the concentrations of which analyte?
a) Cholesterol
b) Triglycerides
c) Phosphorus
d) Urea

Answer 3

a) Cholesterol

Question 4

Answer 4

Question 5

Answer 5

Background: Use of NO tubes at home could reduce cost and facilitate enteral feeding until recovery of appetite
Population: 119 animals 90 cats and 29 dogs, discharged wth NFT for minimum 24hrs
Results: Feedign tubes in place for median 6d (1-17), 62% animals recovered appetite whilst wearing NFT, complication rate 65.5%, only 18.5% required a consultation with no life threatening complications. Owners satisfied in 94% cases
Conclusion: Many complications, althogh no major adverse effects reported and NFT were easily handled by owners

Question 6

What complication rate was observed in dogs and cats managed at home with naso-oesophgeal feeding tubes?
a) 35.5%
b) 45.5%
c) 55.6%
d) 65.5%

Answer 6

d) 65.5%

Question 7

Answer 7

Question 8

Answer 8

Objective: Randomized, blinded, controlled trial. To compare a hydrolsed fish diet with/without probiotics and cobalamin (HF/HF+) to a limited ingredient diet in dogs with non PLE CE and dogs with PLE
Population: 31 dogs wth CE 23 non-PLE and 8 PLE
Results: 19/23 (83%) non-PLE dogs responded to initial diet. There was no difference between diets. 4/4 non-responders responded to another diet with sustained remission of 18/19 at 26 weeks. Serum cobalamin was increased and maintained by diet. Sermu folate decreased but was normalised and maintained by diet.
Conclusion: Changing diet, independent of antigen restriction or supplemental ingredients, induced remission in dogs with non-PLE CE. Serum cobalamin and folate concentrations were maintained by diet. Hydrolyzed fish diets supported clinical recovery and remission in PLE.

Question 9

Hydrolysed fish diets have been associated with which of the following in dogs with PLE?
a) increased serum albumin
b) increased serum folate
c) decreased serum B12
d) improved faecal consistency

Answer 9

a) increased serum albumin

Question 10

Answer 10

Question 11

Answer 11

Background: melanocortin 4 antagonist TCMCB07 is safe and effective in reversing cachexia caused by sepsis or cancer in rodents and in healthy beagle dogs.
Population: 14 dogs with cachexia of any cause except GIT/oral neoplasia
Results: All dogs completed the trial. Significant changes: Increased mean body weight, increased body condition score and WSAVA muscle condition and increased BUN. owners perceived their dogs were panting less and had an improvement in general health. 4 dogs had coat pigment changes. Peak plasma concentrations were similar to healthy dogs
Conclusion: TCMCB07 was safe and has potential efficacy in dogs with cachexia

Question 12

What change may be observed on physical examination with long term administration of TCMCB07 for management of cachexia?
a) Alopecia
b) Change in coat pigmentation
c) Worsening muscle condition score
d) Loss of nails

Answer 12

b) Change in coat pigmentation