Nutrient digestion and absorption 1 Flashcards
what are carbs needed for?
main energy source in the body
Simplest carbohydrate/which one can be absorbed into the body
Monosaccharides
3 monosaccharides taken up by the body are glucose, galactose and fructose- hexose sugars
What are disaccharides and main ones
Two monosaccharides linked together via a glycosidic bond
Lactose= glucose +galactose– broken down by lactase
Maltose= glucose+ glucose– broken down by maltase
Sucrose= fructose + glucose– broken down by sucrase
Starch
- plant storage form of glucose
- L-amylose + amylopectin
- L- amylose= glucose in straight chains
- amylopectin= chained glucose with alpha 1,4 glycosidic bonds
what can break down alpha 1,4 glycosidic bonds?
amylase
Cellulose
- makes up plant cell walls- makes them stand
- straight chain glucose with beta 1,4 glycosidic bonds- -
- cannot be broken down by enzymes in the body
- only cellulase can break it down
Glycogen
- animal storage form of glucose
- linked by alpha 1,4 glycosidic bonds
- 18 miles worth of glycogen in the body
How is glucose taken up?
1- glucose and sodium taken up through apical membrane together through SGLUT1
2-inside cell sodium transported out through basolateral membrane via sodium-potassium pump
3-Glucose transported out of basolateral membrane via the GLUT-2 transporter
4- As a result of sodium being transported into the blood so is H20 through the tight juctionns
How is galactose taken up?
same as glucose
how is fructose taken up?
GLUT-5 in
GLUT-2 out
Does not require sodium- so no movement of h20
How are proteins broken down?
peptidases and proteases
EXO/ENDO
EX0= at the end-one by one
-amino
-carboxy
ENDO= in the middle
Absorption of amino acids?
- aminoacid and sodium taken up by SAAT1
- h20 taken up
Absorption of dipeptides and tripeptides
In acidic microclimate- Ph<6
Through PEPT1
Na taken up through NHE3
Structure of the SI
- Microvilli
- Held together by adhesive junctions and tight junctions
- 2 membranes- apical and basolateral
- Digestive enzymes at brush border
- Membrane is lipid soluble so water soluble molecules need to be transported through using vectorial transport