Nutrient Digestion 2 Flashcards

1
Q

WHat enzyme digests fat in small intestine

A

pancreatic lipase

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2
Q

Are triacylglycerols soluble in water?

A

no

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3
Q

What does triacyglycerol break into?

A

Monoglyceride and 2 fatty acids by the enzyme lipase

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4
Q

What is emulsification?

A

Dividing a large droplet into smaller droplets in order to increase surface area and accessibility to lipase action

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5
Q

Emulsification requires two things, what are they?

A

Mechanical disruption: by smooth muscle contraction

Emulsifying agent: to prevent small droplets from forming into large droplets again

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6
Q

What is in bile

A

bile salts and phospholipids and ampiphatic molecules

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7
Q

What are micelles

A

smaller droplets of emulsion that act liek a “fat taxi” and never enters cells.
Consist of : Bile salts + Phospholipids + Monoglycerides + Fatty acids
They are polar portions on the outside and non polar on the inside

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8
Q

When micelles breakdown, what do they release

A

small amounts of free fatty acids and monoglycerides that diffuse across plasma membranes

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9
Q

What happens after fatty acids and monoglycerides enter epithelial cells

A

enters smooth endoplasmic reticulum where they are reformed into triacylglycerols

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10
Q

Triacylglycerols emulsified by?

A

Amphiphatic protein

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11
Q

chylomicrons are

A

extracellular fat droplets that also contain phospholipids, cholesterol & fat-soluble vitamins

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12
Q

where do chylomicrons pass by

A

lacteals between endothelial cells

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13
Q

What are the water soluble vitamins

A

B group, C and folic acid

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14
Q

How are water soluble vitamins transported?

A

Passive diffusion or carrier-mediated transport

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15
Q

How does b12 absorb into body

A

Binds to intrinsic factor in stomach to form complex which is absorbed via specific transport mechanism in distal ileum.

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16
Q

what does b12 deficiency cause

A

pernicious anaemia

17
Q

how does iron transport from lumen to blood

A

via DMT1 into duodenal enterocytes

18
Q

How are iron ions stored in cells

A

as ferritin

19
Q

iron in blood binds to:

A

transferrin