Large Intestine Structure and Function Flashcards

1
Q

What layers in muscle are complete and incomplete in the large intestine

A

Circular muscle layer complete but longitudinal layer incomplete

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2
Q

What spans the entire length of colon

A

Teniae coli

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3
Q

What do contractions of teniae coli cause

A

Haustra or pouches that give it a puckered appearance

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4
Q

What is the mucosa made out of

A

Simple columnar epithelium cells

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5
Q

Does the large intestine have crypts and goblet cells

A

Yes for mucus secretions

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6
Q

What mucosa is found in rectum

A

Simple columnar epithelium

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7
Q

How is the muscularis externa of the rectum compared to rest of GI tract

A

Thicker

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8
Q

What muscle makes up

External anal sphincter

A

Skeletal muscle

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9
Q

What epithelium found in anal canal

A

stratified squamous

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10
Q

What does the colon do

A

Transport of sodium to blood followed by water to dehydrate chyme

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11
Q

Bacterial fermentation products result in:

A

Short chain fatty acids for energy
Vitamin K (blood clotting)
Gas (Flatus) - N,CO2,Hydrogen

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12
Q

Defaecation reflux controlled by:

A

Parasympathetic control via pelvic splanchnic nerves

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13
Q

Give ex of enterotoxigenic bacteria

A

vibrio cholerae and escherichia coli

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14
Q

what do Enterotoxigenic Bacteria produce

A

protein enterotoxins which maximally turn on intestinal chloride secretion from crypt cells and this increases H2o secretion causing diarrhoea

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15
Q

What intracellular second messengers do Enterotoxigenic Bacteria
activate

A

Calcium
cAMP
cGMP

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16
Q

How do you treat secondary diarrhoea

A

Simple salt and glucose solution. This makes water re renter the blood stream thorugh SGLT1 transporters and water follows