NUR 240 ch 23 CAD Flashcards
Atherosclerosis
the abnormal accumulation of lipid deposits and fibrous tissue within arterial walls and lumen
coronary atherosclerosis
blockages and narrowing of the coronary vessel reduce blood flow to the myocardium
what causes the symptoms in atherosclerosis
myocardial ischemia (tissue death, no blood flow)
symptoms of atherosclerosis
angina pectoris, pain that radiated to jaw or left arm, shortness of breath
atypical in women- epigastric pain, low back pain
modifiable and nonmodifiable risk factors for CAD
nonmodifiable:
- family history of CAD
- increasing age
- gender (men develop earlier than women)
- race (higher among African Americans)
- history of premature menopause
- primary hypercholesterolemia
modifiable:
- hyperlipidemia
- tobacco use
- HTN
- diabetes
- metabolic syndrome (elevated LDL, low HDL)
- obesity
- physical inactivity
- chronic inflammatory disease
- chronic kidney disease
LDL levels
100-129
HDL levels
above 40
how can we prevent CAD
control cholesterol level
dietary (reduce sodium, mediterranean diet)
physical activity
medications
smoking cessation
HTN management
control diabetes
Cholesterol medications (first line for CAD)
lipid lowering agents:
3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) (or statins)
nicotinic acids
fibric acids (fibrates)
bile acid sequestrates (resins)
cholesterol absorption inhibitors
omega-3 acid-ethyl (esters)
atorvastatin (lipitor)
used to lower bad cholesterol and reduce the risk of stroke, heart attack, and other heart and blood vessel problems
monitor liver enzymes (medication is hepatotoxic and processed through the liver)
types of angina
typical (stable) angina
unstable angina
typical angina
predictable and consistent pain that occurs on exertion and is relieved by rest and/or nitroglycerin
unstable angina
symptoms increase in frequency and severity; may not be relieved with rest or nitroglycerin
clinical manifestations of angina pectoris
pain or discomfort is poorly localized and may radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, usually the left arm. tightness or a heavy choking or strangling sensation
weakness or numbness in the arms, wrists, and hands, as well as shortness of breath, pallor, diaphoresis, dizziness or lightheadedness, and nausea and vomiting
angina pectoris in older adults
dyspnea is often the presenting symptom
silent CAD
object of medical management of angina pectoris
decrease oxygen demand of the myocardium and to increase the oxygen supply