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RAD fun > Nuke MA > Flashcards

Nuke MA Flashcards

1
Q

I-131

A
  • Beta particles. beta emission decay
  • t1/2: 8 D. Gamma photons: 364 KeV.

Both Beta and long t1/2 > high rad

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2
Q

I-123

A
  • Decay by Electron capture
  • Gamma Kev: 159. t1/2: 13 Hr
  • no alpha or beta particles
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3
Q

RAIU thyriod N uptake

A

4HR: 6-15%

24 HR: 15-30%

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4
Q

decreased thyroid RAIU DDX

A
  • 1ry, 2ry hypoT
  • excess T4 2/2 meds, strumi ovari, factitious
  • amiodarone tox
  • subacute thyroditis&raquo_space; PAINFUL
  • postpartum thyroditis
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5
Q

I131 doses:

A 
Graves: 10-15 mCI 
T MNG ot T nodule: 15-30 mCI 
thyriod ca local: 30-100 mCI 
LAD: 100-200 mCI
mets > 200 mCI
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6
Q

postpartum I2 Rx

A
  • start 6 wk after delivery to decrease concen of I2 in the br
  • give Dop agonist to decrease I2 dose to the br
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7
Q

I2 WBS - ve. +ve TG next?

A

FDG only if TG > 10

TG < 2 less likely recurrance

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8
Q

FDG for thyroid ca

A

+ve: De-differ PTC, FTC. anaplastic, hurthle cell, MTC

-ve: DIFFER. PTC, FTC

+ve MTC ( FDG, In111-Oct (not the best but 1st line), Ga67-Dotatate, I2 if DE-DIFFER)

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9
Q

MIBG med interaction

A 
CCB
labetolol ( other BB r ok)
TCA. 
sympatho ( -ephidrine, phenylephrine)
reserpine
Insulin
cocaine

aplha blocker is ok

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10
Q

In-OCT negative in

A

insulinoma. less SN in MTC

+ve
meningoma, glioma, RCC, BCA, SCLC

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11
Q

Tc99-MDP and NaF attach to

A

Ca hydroxypetiate

STx calc ( myositis) attach to CaPO4

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12
Q

Ewing sarcoma mets on BS

A

no positive uptake on BS. but OS does

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13
Q

mmc 3 sites Pagets

A

Pelvis > spine > skull

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14
Q

Hyperostosis frontalis

A
  • inner table expansion
  • Women&raquo_space;» Male
  • +ve in BS
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15
Q

Hypertrophic Osteoarthopathy DDX ?

A
  • LCa: mcc
  • COPD
  • IBD
  • Li. diz
  • CHF
  • Hypoexia

Both periosteal reaction + cortical thickening

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16
Q

SOC for posible infected prosthesis

A

In111-WBC + TC99-SC

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17
Q

Mets calc sites & DDx

A 
- thyroid, lung, GI, GU, heart. 
DDx: 
- CRF
- MM
- parathyriod tum
- high vit D.

Free pertchn: only thyriod and stomch

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18
Q

BMD

A
  • T score: compare 2 young, same sex, ethic ( done in old pt )
  • Z score:compare to same age, sex sex & ethnic ( done in young pt)
  • most reproducible site adult: spine > total hip > NON dominat radius
  • most reproducible site children: PA spine, total body less head
19
Q

DDx of increased renal uptake on BS

A 
CTX
ATN
SCA
high Ca 2/2 PTH
necrosis
iron
20
Q

When do u use Z or T score.

A

Z score for young pt < 50 YO, pre- M W
T score: > 50. Post-M W.
ab Z score < 2 for expected age

21
Q

BMD response to Rx & hip fracture risk

A

1 - Rx: spine

2- Hip fracture risk : total hip measurement

22
Q

most Sen study to eval NB mets

A

MIBG > BS

MIBG + BS > MIBG alone

23
Q

Radium-223

A

Alpha particle
< 100 um
decrease bone pain + increase survival
GI excretion > diarrhea

24
Q

Stonium-89

A

beta particle
7.2 mm
urine exc

25
Q

Smartium-153

A

beta
Max E: 0.81 MEV allow gamma emission img
photo peak: 0.103 MEV

26
Q

TC-HMPAO

A
  • peak activity in few min
  • rapid washout.
  • F, thalamus, Cerebellum.
  • img: 30-60 min after IV
27
Q

Tc-ECD

A
  • peak activity in few min
  • slow washout. more rapid clearance from bl. pool
  • Occipt, parietal.
  • img: 30-90 min after IV
28
Q

extratemp seizure most Sn test

A

Ictal perfusion HMPAO

Interictal FDG is NOT

29
Q

FDG PET VS SPECT FOR sizure

A

FDG pet: higher SR. lower BG activity, poor temp R.

30
Q

FTD vs advanced AD

A

beta amyliod

florbetapir
florbetaben
flutemetamol

ab first in amyliod then FDG

31
Q

I123-ioflupanae is analog to

A

cocaine

presynaptic D terminal

32
Q

Warthin tumor +ve in

A

Tc-pert
octeriotide
FDG

Adenoid cystic only with FDG

33
Q

Med ass w/ FP gastric emptying study

A

CCB
anticholinergic
opioid
antacid

34
Q

free pertch

A

gastric mucosa
thyr
salivary g
GU

35
Q

FN hemang study on RVC scan

A

small < 1.0 cm on SPECT. < 3 cm on planer
fibrotic
adj to vessels

36
Q

critical organs for disofenin/mebrofenin

A

GB

37
Q

critical organs for Tc99-sestambi/tetrofosmin in cardiac img

A

GB wall

38
Q

critical organs for TC99 RBC

A

SP. heart

39
Q

critical organ for SC and In-WBC

A

Sp

40
Q

CCK dose

A

0.02 ug/kg/60 min

41
Q

delayed biliary to bowel transit time

A 
CH GB diz
meds: opiates, CCB, BZD, H2 blocker, OCP, progestrone, octerotide, indomethacin, theophiline
DM
obesity
pregnancy
WNL
vagotomy
42
Q

radioisotope for remal func in kids

A

MAG-3 2/2 GFT is not comp developed in neonates so DTPA does not work.

43
Q

Differnational renal fun

A

DMSA disregard hydro

MAG-3 w/o hydro

RAD fun (17 decks)

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