CNS Flashcards
maturation pattern in neonate
reach adult T1 in 1 yr
adult T2 in 2 yr
inf > sup
post > ant
cent > periphr
sens > motor
what is the last part of the brain mylinate
subcortical WM.
occipt > 12 mo
front > 18 mo
FT finsih > 40 mo
PS: BS and post IC > mylinated at birth
MC anomaly ass w/ ACC
IH lipoma
mcl: IH 2nd: Quadriq cistern
not tru neoplasm. cong
Iniecephaly
extreme retrofelx of the head = star gazing fetus
large for mag
visceral anomaly
short neck
Rhombencephalosynapsis
absence of the vermis and continuity of the cerebellar hemispheres, dentate nuclei, and superior cerebellar peduncles.
DW varient vs DWM
vermis is hypoplastic in both
vs. DWM:
cerebellum is hypoplastic
no marked hydro
post. fossa is normal in size
meckel gruber syndrome
occiptal enchepahlocele
polycystic kid
polydactyl
holoprosnch
azygous ACA
lobar HPE
SOD
SOD
ab. SP
ab. optic tract
schizencephaly
Dyke-Davidoff-Masson syndrome
unlike Ramussen’s encph
there is calv expansion and sinuses pneumotization
mildest form of lissencphaly
double cortex band hetrotopia
Xlinked, F>M
classic one is autosomal. M=F, CMV
cobblestone lissencephaly
overmigration.
ass w/ congenital muscular dysplasia
retinal detach
hydranencephaly causes
HSV is the mcc
2nd: toxo, CMV
IH hypotension
Downward displacement of brain through incisura (brain "sagging") Diffuse dural thickening/enhancement Veins, dural sinuses distended Engorged pituitary gland Subdural hygromas/hematomas
mcl of arachniod cyst
middle cranial fossa
NB mets in kids
orbit
skull
dura
NOT BRAIN
Pleomorphic Xanthoastrocytoma
cortical based, periphral, solid and cyst Temporal lobe mcl Supratentorial enhancing dural tail, no T2 edema peds = DIG
Dysembryoplastic neuroepithelial tumor (DNET)
Benign mixed glial-neuronal neoplasm focal cortical dysplasia T lobe >> drug resistant seizure bubbly appearance > NO C+ peds < 20
Oligodendroglioma
F lobe
1p/19q deletion > gd px
IDH1 > T2/flair mismatch
medulloblastoma ass w/
Turcot syn: GBM
Gorlin syn: basal cell navus skin ca, odontogenic cyst
mcc of IV mass in adult
central neurocytoma
|»_space; calcify, hetrogen, cystic and solid
mcl of subependymoma
4th vent, foramen of monro
homogen C+
might not enhance
soft»_space; no hydro
choriod plexus pap/ca
ca only in kids.
adult = 4th vent
Meningoma in nuke
+ octerotide
+ Tc-MDP
mcl of dermiod cyst
1st: supracellar cistern
2nd: post. fossa
NF-2
Hemangiopericytoma
sarcoma
mimic aggressive mening
invade skull» but no calc no hyperostosis
dysmoplastic infantile ganglioma
large cystic
supraten
< 1yr.
one lobe
NPH
> 0.3 evans index
LP: drainage of 30-40 ml
porenchephalic cyst
WM lining the cyst
mcc: 2/2 to periventricular hge infarct
perivent leukomalacia
wavy countors of lat ven
low vol of WM
ab SI
Joubert synd
ARD
molar teeth is high Sn but not Sp. for joubert
molar teeth means»_space; ataxia, develop delay and hypotonia
ACC is WNL
- up to 18 wk GA. you cant Dx ACC before that
- agyric smooth app of the brain WNL until 26 GA
psuedotum cerebri LP pressure
> 25 mmHg
TRV sinus stenosis is seen up 90%mc
mc ass w/ SOD
schizonepchaly
earliest manifestation of osmotic demylination
+DWI pons
extrapontine loc might be seen: BG, EC, amygdala, cerebellum
Marchiafava-Bignami disease (MBD)
- is a rare CNS disorder
alcoholism and malnutrition. - classically involves the corpus callosum with necrosis and demyelination. no ME.
- notice WE does not involve CC
methanol toxcity
optic nerve atrophy
hge putamen
WM necrosis
CO
GP hypoHU.
T2 bright
mc CNS tumor post RTX
meningoma
mc brain changes post RTX
vascular mal
cavernoma/teleangectasia
Chasing the dragon
Herion
semiovale WM. PL of IC, deep cerebellum WM
mcl of MS in children
post. fossa.
M = F
most Sn seq for spine and infratent MS
T2
subcortical arteriosclerosis encephalopathy
multi infarct dementia that involves the WM. spares U fibers
old
HTN
CADASIL
< 40 YO mc heredidatry stroke T lobe >>> classic F and P lobes can be + spares occipital L.
Hurler’s diz
lysosomal beaked L1 VB metopic carcniosyn prominant perivascular space macrocephaly
MELAS
maternally inhertied
mitoch dis
elev lactate in spectro
involves P-O lobes
metachromatic leukodystrophy
AR lysosomal
non SP WM + spares U fibers
X-linked leukodystrophy
P-O WM
canvan diz
AR, neonate, poor head control, hypotonia High NAA diffuse WM involve GP thalami spares putamen
congenital HIV
BG Ca⁺⁺ in (not in adult)
Cerebral atrophy»_space; frontal
fusiform vasculopathy stroke
subarachnoid hemorrhage
congenital HSV encephalitis
hge encephalitis vs Rubella»_space; ischemia
cryptococcus
Dilated PVSs in deep gray nuclei of AIDS patient, no enhancement
Brain TB
basilar C+
hydrocephalus
vasculitis»_space; infarct
CN involve
Most Sn seq for HSV
DWI > T2
you might see bleeding in the adult type
west nile
T2 bright BG and thalamus
hge
pt from saudi
CJD = prion diz
Pulvinar sign: post thalamus
Hockey stick sign: dorsomedial tthalamus
rapidly progressive atrophy
gyriform DWI+
mcc of epi/subdural empyema
frontal sinusitis
cephalohematoma
subperiosteal hematoma
elevate the periostum. limited by stutures
no CL Sg.
mcl: P and O lobes
subgalaeal hematoma
not limited space.
underneath galeal aponiorosis
sutural diastesis comp in adult
dural venous sinus thrombosis
kids: leptomeningeal cyst
mc parasitic diz of the CNS
neurocystoscreosis
stage I vesicular: no edema or C+, cystic
stage II colliodal: edema C+
stage III grandular less edema and C+. start to calc
stage IV: nodular calcified: calc
non ketoic hyperglycemia
BG and BS CT hyperdensity
T1: high
no ME, no C+
looks similar to HE. look at Hx
WE
spares BG in adult
common in children