nuclic acids Flashcards

1
Q

the major steps involved in handling genetic information are illustration by

A

the central dogma of molecular biology

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2
Q

genetic information is stored in the

A

base sequence of DNA molecules

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3
Q

A gene is

A

a unit of DNA that encodes a particular RNA molecule of a protein

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4
Q

name the chemotherapeutic agent that target S-phase of cell cycle

A

methotrexate, 5-fluorouracil, hydroxyurea

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5
Q

name the chemotherapeutic agent that target G2-phase of cell cycle

A

bleomycin

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6
Q

name the chemotherapeutic agent that target M-phase of cell cycle

A

Paclitaxel, vincristine, vinblastine

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7
Q

name the non cell-cycle specific chemotherapeutic agent

A

cyclophosphamide, cisplatin

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8
Q

control of the cell cycle is accomplished at checkpoint between the various phases by the proteins such as

A

cyclins and cyclin-dependent kinases

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9
Q

what is the function of check point

A

ensures that cell will not enter the next phase of the cycle until the molecular event in the previous cell cycle phase are true and completed

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10
Q

what is reverse transcription

A

production of DNA copies of RNA

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11
Q

reverse transcription is commonly associated with the life cycle of

A

retroviruses

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12
Q

reverse transcription is catalysed by

A

reverse transcriptase

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13
Q

what is the role in reverse transcription in human cells

A

role in amplifying certain highly repetitive sequences in the DNA

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14
Q

phosphate grp and OH grp are found in which end of DNA

A

P - 5’
OH - 3’

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15
Q

name the RNA that forms a cloverleaf structure that contains many unusual nucleotides and anticodon

A

tRNA

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16
Q

in which organism we can see ssDNA genome and some dsRNA genomes

A

certain viruses