nuclic acids Flashcards
the major steps involved in handling genetic information are illustration by
the central dogma of molecular biology
genetic information is stored in the
base sequence of DNA molecules
A gene is
a unit of DNA that encodes a particular RNA molecule of a protein
name the chemotherapeutic agent that target S-phase of cell cycle
methotrexate, 5-fluorouracil, hydroxyurea
name the chemotherapeutic agent that target G2-phase of cell cycle
bleomycin
name the chemotherapeutic agent that target M-phase of cell cycle
Paclitaxel, vincristine, vinblastine
name the non cell-cycle specific chemotherapeutic agent
cyclophosphamide, cisplatin
control of the cell cycle is accomplished at checkpoint between the various phases by the proteins such as
cyclins and cyclin-dependent kinases
what is the function of check point
ensures that cell will not enter the next phase of the cycle until the molecular event in the previous cell cycle phase are true and completed
what is reverse transcription
production of DNA copies of RNA
reverse transcription is commonly associated with the life cycle of
retroviruses
reverse transcription is catalysed by
reverse transcriptase
what is the role in reverse transcription in human cells
role in amplifying certain highly repetitive sequences in the DNA
phosphate grp and OH grp are found in which end of DNA
P - 5’
OH - 3’
name the RNA that forms a cloverleaf structure that contains many unusual nucleotides and anticodon
tRNA