Nucleotide Mutations Flashcards
What is a mutation?
A random change in the DNA
What is a single gene mutation?
The alteration of a DNA nucleotide sequence as a result of the substitution, insertion or deletion of nucleotides
What results in a frame-shift mutation?
Nucleotide insertions or deletions
What is substitution?
When DNA nucleotide bases are switched for a different nucleotide base and only one amino acid is altered
What is deletion?
When a DNA nucleotide base is deleted from the nucleotide sequence.
Every amino acid after point of deletion will be put out of sequence
What is insertion?
When a DNA nucleotide base is added to the nucleotide sequence.
Every amino acid after point of insertion will be put out of sequence.