Nucleic Acids Flashcards
Two types of nucleic acid
DNA
RNA
Freidrich Meischer
1869
First crude purification of DNA, leukocytes as source matl
“nuclein”
Nucleotides
Building blocks of nucleic acids
The perfect trio of the Nucleotide Structure
Phosphate
Sugar
Base
Purine bases
Adenine (A)
Guanine (G)
Pyrimidine bases
Cytosine (C)
Thymine (T)
Uracil (C)
Phosphodiester bond
- covalent
- bond b/w two sugar groups and a phosphate group
- forms the sugar-phosphate-sugar backbone of DNA & RNA
- links two nucleotides together to form DNA & RNA
Difference between DNA & RNA
No oxygen is bonded in C2
Phosphate group joins which C in the sugar phosphate backbone?
The phosphate group joins C3 of one sugar and C5 of the sugar next in line
The bases are attached to which C in the sugar phosphate backbone?
Carbon 1
The order of the bases determines the genetic information of the molecule
Bond between sugar and nitrogenous base
Beta n glycosidic bond
Bond between sugar and nitrogenous base
Beta n glycosidic bond
Bond between sugar and nitrogenous base
Beta n glycosidic bond
