Nucleic Acid Synthesis Inhibitors Flashcards
0
Q
MOA of Trimethoprim
A
Srlective inhibitor of bacterial dihydrofolate reductase
1
Q
MOA of Sulfonamides
A
Becteriostatic inhibitors of folic acid synthesis by competitively binding to dihydropteroate synthase
2
Q
Short acting sulfonamide
A
Sulfisoxazole
3
Q
Intermediate acting sulfonamide
A
Sulfamethoxazole
4
Q
Long acting sulfonamide
A
Sulfadoxine
5
Q
MOA of Fluoroquinolones
A
Interferes with topoisomerase II (DNA gyrase) in Gm (-) bacteria and topoisomerase IV in Gm (+) bacteria