Antibiotics Flashcards
Coverage of Pen V
Streptococcal, pneumococcal, meningococcal, and syphilis
MOA of beta lactam antibiotics
Inhibits transpeptidation reaction that cross-links the linear peptidoglycan chain constituent of the cell wall
Antipseudomonal Penicillins?
Ticarcillin, Carbenicillin, Piperacillin
First generation cephalosporins
Cephalexin Cephapirin Cephradine Cephalothin Cefazolin Cefadroxil
Second generation cephalosporins
Cefoxitin
Cefuroxime
Cefotetan
Cefaclor
Cefoperazone is a __________ generation cephalosporin
3rd
Example of 4th generation cephalosporin
Cefipime
Coverage of Cefipime
Gram positive and gram negative
T/F: Cefipime is resistant to beta lactamase
True
Antipseudomonal cephalosporins
Ceftazidime
Cefepime
Cefoperazone
Drug class of imipenem, ertapenem, and meropenem
Carbapanem
Drug class of aztreonam
Monobactam
Used for infections resistant to beta-lactamases produced by gram negative rods, including Klebsiella, Pseudomonas and Serratia
Aztreonam
What is the possible side effect if Vancomycin was given too fast via IV?
Red man syndrome
Drug class of Vancomycin
Glycopeptide
MOA of Vancomycin
Inhibits cell wall synthesis by binding to the D-Ala D-Ala terminus of nascent peptidoglycan
Drug class of Chloramphenicol
Protein synthesis inhibitor
Causes grey baby syndrome
Chloramphenicol
Idiosyncratic effect of Chloramphenicol
Aplastic anemia
Premature baby had history of unrecalled antibiotic intake, presents with ashen gray skin, cyanosis and cardiovascular collapse, lab findings revealed decreased RBC. Diagnosis?
Gray baby syndrome due to chloramphenicol intake