Nucleic Acid & Gene Structure Flashcards
What are the two types of nucleic acids?
- DNA - deoxyribonucleic acid
2. RNA - ribonucleic acid
What is the structure of a nucleotide?
- Nitrogenous base
- 5-carbon sugar
- Phosphate
What are the two classes of nitrogenous bases?
- Pyrimidines
2. Purines
What are the THREE pyrimidines?
- Cytosine
- Thymine (in DNA)
- Uracil (in RNA)
What are the TWO purines?
- Adenine
2. Guanine
How do the ribose sugars differ in DNA and RNA?
H group on 2’ in DNA
OH group on 2’ in RNA
What is the bond called when linking 3’-hydroxyl group of one nucleotide to 5’-phosphate group of the next nucleotide?
3’-5’ phosphodiester bond
What is the directionality of nucleic acids?
5’ to 3’
How many H bonds are between C and G?
3
How many H bonds are between A and T?
2
What is a gene?
A segment of DNA that codes for a protein or RNA molecule
What are Introns and Exons?
INTRONS - non coding sequence of DNA
EXONS - coding sequence of DNA
Where are Introns and Exons found?
In the PRIMARY RNA TRANSCRIPT
What is splicing?
The removal of the introns in a gene and joining together of the exons