Amino Acids Flashcards

1
Q

How many standard amino acids are there?

A

20

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2
Q

Describe the structure of a standard amino acid

A

Central carbon (alpha) bonded to a hydrogen, an R (side chain) group, a carboxyl group and an amino group

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3
Q

Which is the only standard amino acid that is attached to more than the central carbon?

A

Proline.
Attached to the central carbon and the nitrogen on the amino group

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4
Q

How many classes of amino acids are there?

A

4 classes:
Hydrophobic
Hydrophilic
Acidic
Basic

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5
Q

What is the name of the smallest amino acid?

A

Glycine

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6
Q

What are the two types of hydrocarbon side chains?

A
  1. Aromatic
  2. Aliphatic
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7
Q

What are the two Aromatic side chains?

A

Phenylalanine and Tryptophan

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8
Q

What is the largest amino acid?

A

Tryptophan

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9
Q

What is the only amino acid to have sulphur in its side chain?

A

Cysteine

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10
Q

What kind of bond can the sulfur group on Cysteine form?

A

Disulphide bond

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11
Q

Name a protein that contains a disulfide bond

A

Insulin

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12
Q

What is the difference between a hydrophobic and a hydrophilic amino acid?

A

Hydrophobic:

  • Has UNCHARGED NON-POLAR side chain
  • Found in the core of a folded protein (away from water)

Hydrophilic:

  • Has UNCHARGED POLAR side chain
  • Found on the surface of a folded protein (near water)
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13
Q

What two amino acids are Acidic?

A

Aspartate and Glutamate

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14
Q

What three amino acids are Basic?

A

Lysine, Arginine and Histidine

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15
Q

How are amino acids linked to form proteins?

A
  • By peptide bonds
  • Through a condensation reaction which results in a loss of water
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16
Q

Peptide bonds are formed between which groups on the amino acid?

A

Formed between a carboxyl group and an amino group

17
Q

Which direction does a POLYPEPTIDE chain run?

A

From the Amino end to the Carboxyl end

(N-terminal to C-terminal)

18
Q

What does a polypeptide chain consist of?

A
  • A regularly repeating main chain or “back bone”
  • Variable part comprised of distinctive side chains