Nuclear acids Flashcards
What is a nucleotide?
The basic building block (monomer) of nucleic acids (DNA and RNA); made of a phosphate group, sugar, and nitrogen base.
Nucleotides are essential for the formation of DNA and RNA structures.
Define a gene.
A segment of DNA that codes for a specific trait (protein).
Genes are the functional units of heredity.
What is semiconservative replication?
DNA replication method where each new DNA molecule has one original strand and one new strand.
This process ensures genetic continuity.
What is the template/pattern strand?
The strand of DNA used as a guide during replication or transcription; bases are matched complementarily.
This strand is crucial for accurate genetic information transfer.
What is a karyotype?
A visual representation of all the chromosomes in a cell, arranged in pairs.
Karyotypes are used in genetic analysis and diagnosis.
Who discovered that DNA carries genetic information?
Griffith
Through the transformation experiment.
What are the base-pairing rules found by Chargaff?
A = T and C = G
Which scientists used X-ray diffraction to show DNA is double-stranded?
Wilkins & Franklin
What did Watson & Crick build?
The first accurate 3D model of DNA
What structure of DNA did Watson & Crick describe?
Double helix structure
Fill in the blank: _______ discovered that DNA carries genetic information.
Griffith
Fill in the blank: Chargaff found that A = T and C = _______.
G
True or False: Wilkins and Franklin showed that DNA is single-stranded.
False
What technique did Wilkins & Franklin use to study DNA?
X-ray diffraction
What is the structure of DNA?
Double-stranded
DNA consists of two strands that coil around each other to form a double helix.
What is the structure of RNA?
Single-stranded
RNA typically exists as a single strand, unlike DNA.
What sugar is found in DNA?
Deoxyribose
Deoxyribose is a five-carbon sugar that is a component of DNA.
What sugar is found in RNA?
Ribose
Ribose is a five-carbon sugar that is a component of RNA.
List the nitrogen bases found in DNA.
- A
- T
- C
- G
These bases pair specifically (A with T, C with G) to form the genetic code.
List the nitrogen bases found in RNA.
- A
- U
- C
- G
In RNA, uracil (U) replaces thymine (T) found in DNA.
Fill in the blank: DNA has _______ strands.
double-stranded
Fill in the blank: RNA is _______ stranded.
single-stranded
What is the primary function of DNA?
Storage of genetic information
DNA carries the genetic blueprint for the development and functioning of living organisms.