💊 NT Release Flashcards
1
Q
Clostridium botulinum
A
Bacteria produces toxin→botulism
Enters terminals +degrades Ach vescicles
ANS + motor fibres are inhibited
Smooth + skeletal paralysis → respiratory ☹
2
Q
Botox
A
↓ conc toxin produces local paralysis
Cosmetic: reduce wrinkles
Clinical: prevent hyperhidrosis
3
Q
Amphetamine
A
Binds to +reverses action of monoamine uptake transporters→ releases NA,dopamine,serotonin
4
Q
Ephedrine
A
Derivative of amph
Decongestant: vasoconstriction of nasal blood vessels
5
Q
Guanethidine
A
Compete w NA for inclusion into vesicles, prevents NA release
6
Q
Clonidine / α-methyl-DOPA
A
Stimulate pre-synaptic α2, ↓ NA release
Used for hypertensive emergencies
