NSAIDs Flashcards
1
Q
What are the main serious side effects of NSAIDs?
A
GI bleed (ulcers and perforation)
CV events like MI and stroke
Renal injury
2
Q
What factors increase the risk of NSAID use?
A
age, polypharmacy, history of peptic ulcers, renal impairment
3
Q
When should PPI be prescribed with NSAID?
A
Patients over 45
Patients at risk of GI bleeding
4
Q
What drugs should you avoid prescribing NSAIDs with?
A
anticoagulant antiplatelets ssri spironolactone bisphosphonates
5
Q
In which patients are the risks of CV events due to NSAIDs higher?
A
Pts with ihd risk factors
6
Q
Which patients are at increased renal risk when given NSAIDs?
A
Those on diuretics, ACEi, ARB
Elderly
T2D
HTN
7
Q
Which NSAID is best to give someone with CV and renal risks of NSAIDs?
A
Naproxen
8
Q
What are some alternatives to NSAIDs?
A
Paracetamol
Topical NSAID
Opioids
Strengthening exercises
