NSAIDS Flashcards

1
Q

NSAIDS

A

non-steroidal anti-inflammatory drugs

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2
Q

Examples of common NSAIDS

A
  1. Aspirin
  2. Motrin
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3
Q

Injury → release of ______(1)____ → ____(2)____, and _____(3)____ pathways

Both lead to ____(4)____ (fever, edema, redness) and _____(5)___.

A
  1. arachidonic acid
  2. prostaglandin
  3. leukotriene
  4. inflammation
  5. pain
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4
Q

Cox enzyme-1

A

acts to help mucosa

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5
Q

Cox enzyme-2

A

acts to produce inflammation

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6
Q

Actions of NSAIDs

A
  1. Relieve pain
  2. Decrease fever
  3. Decrease inflammation
  4. Anti-coagulant
    1. Stop using these 2 weeks before surgery
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7
Q

1 S/E of NSAIDs

A

gastrointestional distress (heartburn, pain, bleeding)

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8
Q

NSAIDs can also cause these S/Es

A
  1. decrease platelet function
  2. tinnitus
  3. allergies (common)
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9
Q

Aspirin

A

Acetylsalicylc acid (ASA)

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10
Q

Actions of aspirin (acetylsalicylic acid)

A
  • analgesic
  • anti-pyretic (fever)
  • anti-inflammatory
  • anti-coagulant
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11
Q

Other names for Aspirin (acetylsalicylic acid)

A
  • Aspirin
  • Ecotrin
  • ASA
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12
Q

1 S/E of Aspirin

A

Stomach upset

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13
Q

Aspirin (acetylsalicylic acid)

  • Should not be given to ____(1)____ <18 years old (_____(2)____) or anyone with ____(3)___ or ulcer
    • New CDC recommendation- formally 17 years
  • Routes: ____(4)___ and ___(5)___
  • Often ____(6)___ with other drugs like _______(7)____.
A
  1. kids
  2. Reye’s syndrome
  3. bleeding
  4. PO
  5. rectal
  6. mixed
  7. cold medications
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14
Q

Ibuprofen

Names

A

motrin

nuprin

advil

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15
Q

Ibuprofen actions

A
  • analgesic
  • anti-pyretic
  • anti-inflammatory
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16
Q

Ibuprofen

What’s missing in action when compared to aspirin?

A

Ibuprofen is NOT highly anti-coagulant

17
Q

Ibuprofen

OTC strength

A

200 mg/tablet

18
Q

Ibuprofen S/E

A

Not many side effects

19
Q

Ibuprofen should not be given to patients with what conditions?

A
  • asthma
  • renal disease
  • hepatic disease
20
Q

Route of Ibuprofen

A

PO only

21
Q

COX-2 Inhibitors also known as

A

Celecoxib (Celebrex)

22
Q
A