Medication- General Terms & Rules Flashcards
Timing of Medications
Onset
Onset = time of the drug to start working within the body
Timing of Medications
Peak
Peak: time when the drug is working its best
Timing of Medications
Duration
Duration: the length of time the drug has a high enough concentration to be “therapeutic”
Timing of Medications
Half-Life
Half-Life: the time it takes for ½ of the drug to be eliminated
Timing of Medications
General rule of a drug’s ½ life
The longer the ½ lifef, the more medication is still in the body
(longer effect)
Goals of Drug Therapy
- Maintain a ______(1)_____ or ______(2)______ of medication in the blood.
- Avoid too ____(3)____ or too ______(4)____ of the drug for the patient.
- _______what it’s suppose to do.
- Therapeutic Index
- Therapeutic Level
- little
- much
- do
Reasons for Treatment with Medications
Have a problem now that needs treatment, meds will cure problem
Acute needs
Reasons for Treatment with Medications
On-going need
Ex. to keep BP under control, birth control, etc.
Maintenance needs
Reasons for Treatment with Medications
Add to body’s actions
Ex: insulin, vitamins
Supplemental needs
Reasons for Treatment with Medications
Keep the patient comfortable, not expecting a cure
Palliative needs
Reasons for Treatment with Medications
Preventative medications
ex: antibiotics for surgery, birth control
Prophylactic needs
Monitoring Medications
The more medications a patient has in his/her system at once the _______(1)_____ chance of drug _____(2)_____!
- increased
- interactions
Monitoring Medications
Drug interactions can be _____(1)_____, ______(2)_____, or _____(3)_____.
- small
- large
- life threatening
Monitoring Medications
Adverse Drug Effect/ Side Effect
Unwanted effects, produced by the therapeutic level of the drug
Monitoring Medications
Characterisitics of Adverse Effects/ Side Effect
- Usually predictable (nausea, drowsiness)
- MD probably won’t change the drug because of the side effects
Monitoring Medications
Toxic Effects/ Poisoning
Avoidable side effect because the dose was too high
Monitoring Medications
Characteristics of Toxic Effects/ Poisoning
- Also called an “over dose”
- Effects are usually exaggerated effect of the desired action
- Will happen in all cases is the dose is high enough
- Ex: Digoxin - slows heart rate…death
Monitoring Medications
Additive Effects
Two medications with similar actions given together
Monitoring Medications
Characteristics of additive effects
- Can often get by with smaller doses of each drug
- Ex: Tylenol & codeine
Monitoring Medications
Synergistic Effects
Two drugs given together that makes the effect greater than if alone
Monitoring Medications
Characteristics of synergistic effects
- Can be good or bad!
- Bad- Valium & alcohol can depress the CNS causing death
- Good- Demerol & Vistaril together give longer pain relief
Monitoring Medications
Anatagonistic Effect
Two drugs given together work against each other so the effect is less than expected
ex: Alcohol and “speed”
Monitoring Medications
Incompatibility
Two drugs given (often mixed in an IV or syringe) together reach chemically to deteriorate the drugs
Monitoring Medications
Characteristics of incompatibility
- May have cloudiness, precipitate (clumping) or change in color
- Ex: dextrose and human blood preservative
Monitoring Medications
Allergic Reaction
A reaction that triggers the person’s immune system
Monitoring Medications
Characteristics of allergic reaction
- Histamine and inflammation are triggered
- Unique to an individual
- Can be mild or life threatening
Pharmacoeconmics
The study of the econmic factors influencing the cost of the drug therapy
What is this an example of?
Performing a cost-benefit analysis of one antibiotic versus another when competing drugs are considered for inclusion in a hospital formulary.
Can a patient afford the specific medication or does another medication have the same treatment outcome data?
Pharmacoeconmics
What is this?
- Accidental or Intentional?
- Ingested or Inhaled?
- Call the Poison Control Center
- Look at “Red Flags for Drug Abuse”
Acute poisoning
What are the 7 parts of a drug label?
DEMAND
- Directions
- Expiration date
- Manufacturer
- Aministration route
-
Name of the drug
- Generic
- Trade
-
Dosage strength
- Amount per pill or per vial (mL)