NSAIDs Flashcards

1
Q

What are the three primary medical reasons NSAIDs are used in animals?

A
  1. Analgesia
  2. Anti-inflammatory
  3. Anti-pyretic
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2
Q

What are the risks of administering NSAIDs and Glucocorticoids simultaneously?

A

Increase likelihood of side effects, esp. GI signs.

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3
Q

Most common side effects of NSAIDs in the dog

A

GI Effects:
Anorexia, V/D, gastritis, enteriti, gastric ulcers/erosions.

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4
Q

What organ system is of most concern when giving an NSAID to an adult cat?

A

Kidney

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5
Q

What are the two types of liver toxicity caused by NSAIDs?

A

Intrinsic: dose dependent: dog gets into pill bottle
Idiosyncratic: we don’t know why

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6
Q

Pros and Cons of using Aspirin for chronic pain in dogs:

A

Pros:
Inexpensive, readily available
Cons:
Incr. risk of Gi irritation/ulceration

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7
Q

Why choose an NSAID over a corticosteroid for post-op pain control?

A

Fewer side effects, do not affect immune system

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8
Q

How do NSAIDs work?

A

Inhibit cyclooxygenase
Newer = cox 2 selective but selectivity is dose dependent and all are non-selective at higher doses.

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9
Q

What is grapiprant?

A

Galliprant
OA drug, highly selective EP4 receptor (Not COX inhibitor)
NSAID

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