NPN Flashcards

1
Q

It is used to monitor renal fxn

A

NPN

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2
Q

Nessler’s Reagent produces

A

Yellow color

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3
Q

Has the highest concentration in the blood

A

Urea

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4
Q

Major excretory product of protein metabolism

A

Urea

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5
Q

Urea is form in the

A

Liver

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6
Q

How is urea reported

A

Nitrogen concentration rather than urea concentration

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7
Q

Formula to get urea concentration

A

Urea N x 2.14

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8
Q

It inhibits urease

A

Citrate and fluoride

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9
Q

Elevated urea in the blood accompanied by renal failure

A

Uremia

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10
Q

Elevated urea in the blood

A

Azotemia

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11
Q

Urea is produced from

A

Protein metabolism

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12
Q

Decrease plasma urea

A

Low protein intake
Severe liver disease

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13
Q

BUN or urea N/ creatinine ratio

A

10:1 to 20:1

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14
Q

High BUN or urea N/ creatinine ratio (>20:1) is associated with

A

Prerenal and post-renal

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15
Q

Low BUN or urea N/ creatinine ratio (<10:1) is associated with

A

Decreased urea production

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16
Q

Proposed reference method for urea and uric acid

A

IDMS

17
Q

_____ is converted into uric acid, normally in the liver

A

Purines

18
Q

All uric acid in plasma is present as

A

Monosodium urates

19
Q

The product of catabolism of the purine nucleic acid

A

Uric acid

20
Q

Anticoagulant of choice for uric acid

A

Heparin

21
Q

Increased plasma uric acid conct

A

Hyperuricemia

22
Q

Decreased plasma uric acid concentration

A

Hypouricemia

23
Q

Complete deficiency of hypoxanthine-guanine phosphoribosyltransferase

A

Lesch Nyhan Syndrome

24
Q

Creatinine concentration is _______ to muscle mass

A

Directly proportional

25
Q

Plasma creatinine is _______ related to GFR

A

Inversely

26
Q

Creatinine is synthesized primarily in _______ from _____,______,_______

A

Liver;
Glycine, arginine, methionine

27
Q

Assess kidney fxn

A

Creatinine measurement

28
Q

Increased plasma CREATININE

A

abnormal renal fxn

29
Q

Increased plasma CREATINE

A

Muscle disease

30
Q

Creatinine+ alkaline picrate=

A

Red orange chromogen

31
Q

Produced in the deamination of AA during protein metabolism and by bacterial metabolism in the lumen of yhe intestine

A

Ammonia

32
Q

Most ammonia in the blood exist as

A

Ammonium ion

33
Q

Spx used for ammonia

A

Venous blood

34
Q

Source of ammonia contamination

A

Cigarette smoking

35
Q

Decreased in absorbance at 340 nm as NADPH is consumed

A

Glutamate dehydrogenase