Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CC > Lipids and Lipoprotein > Flashcards

Lipids and Lipoprotein Flashcards

1
Q

Lipids are Commonly referred to as

A

Fats

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Lipids is composed mainly of

A

C-H bonds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Considered primary source of fuel

A

Lipids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Lipids requires _____ for circulation in the blood

A

Lipoprotein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Linear of CH bonds that terminate with a carboxyl group

A

Fatty acids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Where does fatty acids mainly derived

A

Hydrolysis of TAG in adipose tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

It is the most important source of energy

A

Fatty acids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Fatty acids are mostly bound to

A

Albumin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Building blocks of lipid

A

Fatty acids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

TAG is also known as

A

Neutral fats

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

It contains 3 fatty acids attached to one molecule of glycerol

A

TAG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

The main storage lipid in man

A

TAG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Similar structure to TAG except they only have 2 fatty acids

A

Phospholipids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Phospholipids are the constituent of

A

Cell membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

3 forms of phospholipid

A

Lecithin: 70%
Sphingomyelin:20%
Cephalin: 10%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Only Phospholipid in membrane that is NOT derived from glycerol

A

Sphingomyelin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Sphingomyelin is associated with px suffetting from

A

Niemann- pick dsx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

An unsaturated steriod alcohol containing 4 rings

A

Cholesterol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

A hydrophilic part of the cholesterol

A

A-ring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Cholesterol is the precursor of

A

Steroid hormones and vitamin D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

2 forms of cholet

A

Cholesterol ester: 70%
Free cholesterol: 30%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Catalyzes the esterification of cholesterol

A

LCAT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What organ synthesizes LCAT

A

Liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Activsfor of LCAT

A

Apo- A1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Enable _____ to accumulate cholesterol as cholesterol ester

A

HDL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Termed to liberate the cholesterol or break ester bond

A

Saponification

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

T or F:
Cholesterol also served as a source of fuel

A

False ( do not serve, because it is not readily catabolized by most cell)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Surface of lipoprotein

A

Cholesterol and phospholipids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Core of lipoprotein

A

TAG and cholesteteryl ester

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Main purpose of lipoprotein

A

To deliver the fuel to peripheral cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Primarily located on the surface of lipoprotein particles

A

Apolipoprotein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Major location of apo a1 and apo a2

A

HDL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Major location of apo b-100

A

LDL and VLDL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Major locatof apo b48

A

Chylomicrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Major location of apo (a)

A

Lp (a)

36
Q

Major location of apo e

A

VLDL and HDL

37
Q

Major location of apo A4, C1-3

A

Chylomicrons, VLDL, and HDL

38
Q

Largest and the least dense lipoprotein

A

Chylomicrons

39
Q

Role of chylomicrons

A

Delivery of dietary fats to hepatic and peripheral cells

40
Q

Appearance of chylomicrons

A

White creamy

41
Q

Major carrier of ENDOGENOUS tag and transfer tag

A

VLDL

42
Q

VLDL is also known as

A

Pre beta lipoprotein

43
Q

Also knows as beta lipoprotein

A

LDL

44
Q

Considered bad cholesterol

A

LDL

45
Q

Increased LDL meanz

A

Increased risk of atherosclerosis and CHD

46
Q

Considered as good cholesterol

A

HDL

47
Q

HDL is also known as

A

Alpha lipoprotein

48
Q

Smallest and most dense lipoprotein

A

HDL

49
Q

HDL has

A

Anti-atherogenic property

50
Q

Reverse cholesterol transport

A

HDL

51
Q

Minor lipoprotein

A

Lp (a)
IDL

52
Q

Lp (a) is also lnowtas

A

Sinkingg pre b lp

53
Q

Ldl like particle that contain 1 molecule of apo(a)

A

Lp (a)

54
Q

Abnormal lipoprotein

A

Lp (x)
Beta-VLDL

55
Q

T or F:
LpX is rich in lipids

A

True

56
Q

LpX is found in

A

Obstructive jaundice and LCAT deficiency

57
Q

Beta VLDL is also known as

A

Floating beta lp

58
Q

Beta vldl accumulates

A

Type 3 hyperlipoproteinemia

59
Q

Dsx associated with abnormal lipid concentration

A

Dyslipidemias

60
Q

Used to describe indiv for whome the cause of hypercholesterolemia is likely multifactorial

A

Polygenic (non familial) hypercholesterolemia

61
Q

Caused by defective or deficient LDL- receptor gene on chromosome 19

A

Famial hypercholesterolemia

62
Q

Familial hypercholesterolemia causes

A

High LDL

63
Q

Accumulation of plasma beta vldl rich in cholesterol and chylomicron remnants

A

Familial dysbetalipoproteinemia

64
Q

Familial dysbetalipoproteinemia is also known as

A

Type 3 hyperlipoproteinemia

65
Q

During ultracentrifugation, Familial dysbetalipoproteinemia is high in

A

VLDL

66
Q

During electrophoresis, Familial dysbetalipoproteinemia is high in

A

LDL

67
Q

Phytosterol are absorbed and accumulate in plasma and peripheral tissue

A

Sitosterolemia

68
Q

Due to defective apo B synthesis

A

Abetalipoproteinemia

69
Q

Abetalipoproteinemia is also known as

A

Bassen-Kornzweig Syndrome

70
Q

Abetalipoproteinemia is associated with

A

Defects in absorption in Fat-soluble vitamin AEK

71
Q

Due to apo b deficiency resulting from point mutation in apo b

A

Hypobetalipoproteinemia

72
Q

Complete absence of HDL due to mutation in the ABCA1 gene on chromosome 9

A

Tangier’s dsx

73
Q

Fish eye disease

A

LCAT deficiency

74
Q

Inability to clear chylomicrons

A

Lipoprotein lipase deficiency

75
Q

Too many chylomicrons in circulation

A

Chylomicron retention dsx

76
Q

Chylomicron retention dsx is also known as

A

Anderson’s dsx

77
Q

Preferred spx for lp assay

A

EDTA plasma

78
Q

Fasting needed for lipids and lipoprotein

A

12-14 hrs

79
Q

End product of Liebermann Burchardt rxt

A

Cholestadienyl monosulfic acid

80
Q

End color of Liebermann Burchardt rxt

A

Green

81
Q

End product of salkowski rxt

A

Cholestadienyl disulfic acid

82
Q

End color of salkowski rxt

A

Red

83
Q

Chemical method of cjolt

A

salkowski rxt
Lieberman Burchardt rxt

84
Q

Reference method fro quantification of lp

A

Ultracentrifugation method

85
Q

Most commonly used support medium

A

Agarose gel

CC (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions