NP(F) Book review- Older Adults Flashcards
Most common cause of dementia and the elderly
Alzheimer’s 60 to 80%
Second most common form of Alzheimer’s
Vascular dementia
Lab tests to rule out other causes of changing level of consciousness when you’re valuating possible dementia
Syphilis, B12, TSH, CBC, heavy metals i.e. mercury
Best imaging when evaluating dementia
MRI
A cognitive exam with the following components- Orientation, short term memory, attention in calculation, recall, writing a sentence, copying a design
Folstein mini mental state exam
A patient scores less <10 on MMSE- what class is this?
Severe
A patient scores 10 to 20 on MMSE, what is this level?
Moderate
A cognitive performance scale that includes the following steps Dash three word recognition, clock drawing, three word recall
Mini cog test
A patient scores four on a mini cog test – how would this be interpreted
No dementia if score 3 to 5
A patient scores one on a mini cog test, how would this be interpreted
Dementia
The sundowning phenomena involves patients becoming agitated, confused, combative in the evening, and resolves in the morning.
Is this seen in delirium or dementia?
Both
The three A’s of Alzheimer’s
Aphasia, apraxia, agnosia
Vascular dementia is also known as
Multi infarct
T/F- Memory loss shows up earlier than executive functioning deficits and Alzheimer’s disease.
True
Alzheimer’s is attributed to The accumulation of ——- &———
And a decrease in what neurotransmitter?
Neurofibrillary plaques
Tangles
Acetylcholine
Parkinson’s is a neurotogenerative disease with Marc decrease of ——— receptors.
Dopamine
What medications are used in the treatment of mild to moderate Alzheimer’s
Cholinesterase inhibitor – they increase acetylcholine synthesis
Ie. Donapezil
What medication may be added to cholinesterase inhibitors in moderate Alzheimer’s
Memantine
First line treatment of Parkinson’s disease
Carbidopa levodopa – dopamine precursor
True or false – sudden withdrawal or dose reductions of levodopa, or dopamine agonist, may be associated with akinetic crises or parkinsonism’s hyperpyrexia syndrome
True
You abruptly reduce the dose of carbidopa levodopa in a patient with Parkinson’s, they report symptoms of fever, autonomic dysfunction, muscular rigidity and altered mental status. What do you suspect is the diagnosis?
Parkinsonism hyperpyrexia syndrome
What is the first line treatment for essential tremor
Propranolol
What vitamin deficiency causes Korsakoff Warneke dementia
B1/thiamine
Essential tremor is an example of what kind of trimmer
Action, or postural tremor
The patient with Parkinson’s is on Levadopa, what lab will you continue to monitor?
B12
What is a common, disconcerting side effect of levodopa
Dyskinesia
Cholinergic drugs can do want to Parkinson’s disease symptoms
Exacerbate/worsen
Drug clearances affected by all of the following except:
A. Renal impairment
B. less efficient liver cytochrome P450 system
C. Malabsorption
D. relatively lower fat to muscle tissue ratio
D- With age there is a relatively higher fat to muscle tissue ratio, which extends half-life a fat soluble drugs.
Initial treatment of COPD
SABA
How to calculate “pack year”
Number of packs smoked per day x Number of years a person has smoked
The flu vaccine and Pneumovax are recommended as primary prevention measure in what patient population?
COPD
True/ False- Decongestants are contraindicated with hypertension in coronary artery disease.
True
Elderly patient with acute onset of severe I pain with headache, nausea, vomiting, haloes around lights, decreased vision.
Acute angle closure glaucoma
On a patient presenting with eye pain, exam reveals a mid dilated pupil that is oval shaped, a cloudy cornea, and cupping of the optic nerve. What is your next intervention?
Referred patient to the emergency department, assume acute angle closure glaucoma
Sudden onset of a shower of floaters, describes looking through a curtain, sudden flashes of light. Name the suspected diagnoses and initial management.
Retinal detachment
Send to ED
Cauliflower like growth + foul-smelling ear discharge + hearing loss on affected side?
Cholesteatoma
Optic disc swollen with blurred edges-
Papilloedema due to increased intercranial pressure
Gradual onset of increased intraocular pressure due to blockage of the drainage of aqueous humour inside the eye causing ischaemic changes to the retina if untreated.
Primary open angle glaucoma – most common type 60 to 70%
Visual changes in primary open angle glaucoma
Gradual loss of peripheral vision
Sudden blockage of a queous humour causing significant increase in IOP resulting in ischaemia and permanent damage to optic nerve - CN II
Primary angle closure glaucoma
Older patient complains of acute onset of decreased/blurred vision with severe eye pain and frontal headache +/- nausea and vomitting
Primary angle closure glaucoma
Leading cause of blindness in the elderly
Age related macular degeneration
Elderly patient who smokes Complains of gradual or sudden and painless loss of central vision in one or both eyes. They report that straight lines appear distorted or curved and that they’re peripheral vision is preserved.
Age related macular degeneration
An older patient with a history of atrial fibrillation complains of sudden onset dyspnoea coughing and rapid heart rate. What’s the suspected diagnosis?
Pulm embolism
What type of normal breath sounds would you expect to hear from the lower and upper lobes?
Lower- vesicular- soft, low
Upper- bronchial- louder
List 3 Conditions that are obstructive pulmonary disfunction
Asthma, COPD, bronchiectasis
List 3 Conditions that are restrictive pulmonary disfunction
Pulmonary fibrosis, interstitial lung disease, diaphragm obstruction
Coughing with excessive mucus prosuction for at least 3 or more months fir a minimum of 2 or more consecutive years
Chronic bronchitis
Permanent alveolar damage and loss of elastic recoil resulting in chronic hyper inflation of the lungs
Emphysema
Impatient with narrow angle glaucoma, BPH, or bladder neck of struction, what class of medications should not be prescribed? (Inhalers)
Anti-cholinergics i.e. Atrovent, spiriva
Medication step up approach in COPD (3)
- SABA +/- SAMA
- LABA or LAMA
- LABA + LAMA
In patients with severe airflow limitations (GOLD 3-4) With frequent exacerbations, what medication’s are indicated for a long-term therapy?
ICS + LABA
When selecting an antibiotic for a patient with COPD, consider coverage against what two bacteria?
Strep pneumo + H.flu
Components of CURB-65-
What score indicates hospital admission-
Confusion, elevated BUN, Resps >30, BP <90/60, older than 65 yrs
>1 = hospital
Pt receives PPSV23, when do recommend the prevnar 13?
8 weeks
If Prevnar 13 first- admin PPV23 1 year after
Peak expiratory flow rate is calculated using what 3 characteristics.
Height, Age and Sex
What TSH and thyroid hormone levels would you expect to see in hyperthyroidism
Decrased TSH
Increased fT3, fT4
Lithium, amiodarone, high doses of iodine, interferon – alpha are all medications that indicate the monitoring of what lab value?
TSH/ thyroid function
What are the classic lab findings of hypothyroidism
High TSH, low fT4
In a patient with suspected Hashimoto’s thyroiditis, what test can be ordered?
Anti- TPO
Name 3 examples of the following- secondary to diabetes
Microvascular changes
Macrovascular changes
Microvascular- Retinopathy, nephropathy, neuropathy
Macrovascular- Atherosclerosis, coronary artery disease
Elderly patient with acute onset high fever, anorexia, nausea, vomiting and left lower quadrant abdominal pain. Possible diagnosis?
Diverticulitis
Describe Rovsing sign
Deep palpation of the left lower quadrant of the abdomen results and referred pain to the right lower quadrant= + rovsing sign
Abdo contents found in RUQ- LUQ- RLQ- LLQ- Supra Pub-
RUQ- liver, gall bladder, ascending colon, R kidney, tail of pancreas
LUQ- stomach, pancreas, descending colon, L kidney (higher than R)
RLQ- appendix, ileum, cecum, R ovary
LLQ- sigmoid colon, L ovary
Supra Pub- bladder, uterus, rectum
Any patient with —— years or more history of chronic heartburn should be referred to G.I. for endoscopy to rule out———.
10 years
Barrets esophagus- precancerous condition
H. Pylori quad therapy
CLAMP
Clarithromycin Amoxicillin Metronidazole PPI X 2 weeks
An older man complains of a headache on his temple, scalp tenderness on the same side, and a sore jaw when chewing that improves when he starts chewing.
Giant cell arteritis
Temporal arteritis treatment
High-dose prednisone for several weeks, refer to rheumatology for management
Up to 20% of patients with a TIA will have a stroke within ——- days, and 25-50% will occur within—-?
90 days
48 hours
FAST mnemonic
Facial droop
Arm weakness
Speech difficult/ dysphagia
Time to call 911
Homonymous hemianopsia-
Test to identify-
Loss of half of visual field- same half missing in both eyes- most common cause is stroke.
Test via visual fields by confrontation
Brocas aphasia –
Warnicke’s aphasia –
Brocas= expressive aphasia- can understand but cant speak
Wernickes= receptive aphasia- cant understand- impaired righting and reading
Ventricular Gallop, aka——-?
S3- heart failure
S3 can be normal finding in who?
Children, pregnant women, and some athletes
Atrial gallop aka ——-?
S4
Which heart sound sounds like
“Kentucky”
“Tennesee”
Kentucky- S3
Tenessee- S4
T/F- S4 in the elderly is always considered pathologic, regardless of symptoms.
False- S4 heart sound aka atrial kick- Can be considered normal in the elderly due to age related increased stiffness in the ventricles. If there are no signs or symptoms of heart/valvular disease it is considered a normal variant.
Systolic Murmurs
MR. ASS
Mitral Regurg/ Aortic Stenosis = systolic
Diastolic Murmurs
MS. ARD
mitral Stenosis/ Atrial Regurg = Diastolic
Where is a split S2 best heard?
Pulmonic area/upper left sternum
What valves cause S1 & S2?
S1- Motivated- mitral, tricuspid- AV valves
S2- Apples- aortic, pulmonic, - semi lunar valves
S3 indicates-
S4 indicates-
S3- CHF
S4- LVHypertrophy
What CHADSVaSC score indicates need for anticoagulation?
2 or more
After changing warfarin dose, it make take up to _ days to see change in INR
3 days
3 possible side effects lf spironolactone
Gynecomastia/galactorrhea
Hyperkalemia
GI sympt (NV diarrhea, stomach cramping)
3 contraindications of beta blockers
Asthma COPD
2/3rd degree heart block (ok in 1st)
Sinus bradycardia
4 Possible side effects of calcium channel blockers
Headaches
Ankle edema
Heart block/ brady
Reflex tacycardia - dihydroperadines ie. amlodapine
Side effects of thiazide diuretics- 3 & 3
Contraindication 1?
Hyper- hyperglycemia + hyperuricemia + hypertriglyceridemia
Hypo- hypokalemia + hyponatremia + hypomagnesemia
Dont give in sulfa drug allergy & anuria
Adult patient complains of an acute onset of an indurated vein, localized redness, swelling, tenderness. Patient is afebrile with normal vital signs.
Superficial thrombophlebitis
First line treatment for superficial thrombophlebitis?
NSAIDS + warm compress + elevate
Normal ABI score?
0.91- 1.3