Endo - Nat Flashcards
__________ hormone is secreted by the parafollicular cells of the thyroid gland and inhibits bone-reabsorption which _________ serum calcium levels
Calcitonin lowers (bone reabsorption refers to the break down of bone by osteoclasts resulting in the release of Ca back into the blood stream)
TSH and TH levels with central hypothyroidism
Both low
TSH and TH levels in hashimoto’s hypothyroidism
High TSH
Low TH
TSH and TH in secondary hyperthyroidism (Ie. tumour)
Both high
Common causes of Euthyroid sick syndrome
Liver disease Renal diease Pregnancy Malnutrition Various medications
Risk Factors for thyroid disease
Age: 50+ in females and 60+ in males
Hx of autoimmune issues
Fmhx of thyroid disease
Neck radiation, thyoroidectomy or radioactive iodine ablation
Lithium or amiodarone
Dietary factors
Chromosomal ab n: Turners, Down, mitochondrial disease
Pregnancy
Which has more opthalamic complications: hypo or hyperthyroidism
Hyperthyroidism: blurred or double vision, dry eyes, conjunctivitis, proptosis, dysconjugate gaze
True or false. Most forms of primary thyroid dysfunction can be detected with TSH testing
True
when should anti-thyroid peroxidase be tested?
Pts with a goitre or mildly elevated TSH to detect for autoimmune thyroididits
what complication of hyperthyroidism are people over the age of 60 more vulnerable to?
Atrial Fibrillations
Starting dose of levothyroixine in the elderly?
12.5 mcg
A) When do people with hypothyroidism start to feel better after starting treatment?
B) How long does it take for symptoms to resolve?
A) 1-2 weeks
B) a few months
Indications for referring to endocrinology with hypothyroidism
Concurrent: cardiac ro endocrine d/o pregnancy or < 18 y.o. Goiter or thyroid nodule poor response to therapy when lab results do not match clinical picture
T/F multinodular goiters and uni-nodular active goiter are more common in older adults than young adults
True
S+S of a thyroid storm
Fever
Tachycardia, afib
CHF
agitation, delirium, coma
