GI - brit Flashcards
Laxatives to avoid or use with caution in elderly
Docusate Magnesium (renal impairment) Mineral oil Soap sud PEG (if impaired gag reflex)
Alarm symptoms of upper GI cancer
weight loss dysphagia persistence of symptoms despite optimal treatment (4-6 weeks) on PPI Odonyphagia IDA
All of the following are risk factors for what type of cancer: >/= 50 years Chronic GERD smoking EtOH increased BMI
Esophageal cancer
All of the following are risk factors for what type of cancer: Family history Gastric polyp H. pylori Previous partial gastrectomy
Stomach cancer
If age > 55 with persistent progression of heartburn or persistent progression of abdominal pain, what is your next step?
Referral
Referral is indicated if < 55 years with absence of alarm symptoms
T/F?
False
What diagnostic tests should be ordered to rule out stomach/esophageal cancer?
CEA serum
CT chest/abd/pelvis
GI tract is frequent site of involvement for ______ it usually involves the stomach
Lymphoma
There is a strong association with _____ and gastric lymphoma
H. pylori
Interpret the following HBV serology
HBsAG -
anti-HBs +
anti-HBC total -
Immune due to vaccination
Interpret the following HBV serology
HBsAG -
anti-HBs -
anti-HBC total -
No evidence of infection, offer vaccine
Interpret the following HBV serology
HBsAG -
anti-HBs +
anti-HBC total +
past HBV infection, immune
Interpret the following HBV serology HBsAG + anti-HBs - anti-HBC total + anti HBc IgM +
acute or chronic hep B infection
T/F?
ALP and GGT may take up to 24 hours to increase?
True
What serum results would lead you to suspect cholestasis and what is the next diagnostic test you would order?
elevated ALP and GGT
Perform abdominal ultrasound to assess biliary tree
If GGT not elevated and ALP elevated, what can you suspect?
May be of bone or placental origin
What to suspect if ALT > 1000U/L
Acute viral hepatitis, hepatotoxin, acute liver injury
What transaminase is most sensitive and specific for hepatitis? Acute increase in this marker can be seen within the first _____ .
ALT
within first 24 hours
AST is produced from: (3)
liver, cardiac, skeletal muscle
If GGT is elevated suspect:
cholestasis or EtOH
If serum LFTs abnormal when to repeat BW or isolated minor abnormality (<1.5 times upper limit of normal)
1-3 months
Diagnostic tests to consider in RUQ pain
AST
ALT
ALP
GGT
If suspect, then abdominal US
If fever –> refer
Define constipation
< 3 stools per week, for > 6 months
Primary causes of constipation (3)
Normal transit
Slow transit
Defecatory dyssynergia
T/F?
Most patients with fecal incontinence do not warrant extensive diagnostic evaluation
True
Early marker of sarcopenia
Decreased grip strength, should be assessed with dysphagia
Stomach acid production in elderly and consequences
Decreased –> decreased empyting, less Ca+ absorption, and changes in med absorption
S&S of constipation
Incomplete emptying
Straining
Lumpy hard stools
Digital maneouvers to relieve symptoms
What two screeners are useful when assessing patient for constipation?
Bristol stool chart
Norgine risk assessment tool for constipation
- https://www.movicol.com.au/files/Constipation-Risk-Assessment-Tool.pdf
List 5 secondary causes of constipation
hypothyroidism hypercalcemia hypokalemia neurologic disorders malignancy rheumatic disease medications
Give an example of a medication that slows transit time for stool
Narcotics Anabolic steroids Anticonvulsants Anticholinergics Antihypertensives TCA
Give an example of a medication that increases transit time and produces hard stools
NSAIDs antidiarrheals antacids Calcium and iron supplements antihistamines
Red flag S&S for constipation
Acute changes in bowels (caliber) Age > 50 IDA Fever Absence of flatus Blood in stool/hematochezia Unexpected wt loss (>/= 10 lbs) Severe abdominal pain, N/V
What examination should be included if patient is experincing abdominal pain, outside of GI/GU and GYNE exam
CVS
BW and diagnostics to consider if presence of alarm symptoms
CBC, serum Ca, TSH, fecal occult testing
Abdominal X ray
Colonoscopy
Fiber dietary intake reccomendations
25-30 g day, increase fiber 5g/day every week (slowly)
Fibre is not recommended in confirmed ______ or ______ constipation
slow transit
pelvic floor dyssynergia
Bulk forming laxative example and how to take
Psyllium, take 1 hour before and 2 hours after other medications, increase intake of fluid
Stool softener/emollient example
NOT advised for patients taking ______
Docusate or mineral oil (increased risk of aspiration)
Not advised for patients on narcotics
Osmotic laxatives examples
Lactulose
Sorbitol
PEG
Mag hydroxide
Caution ___ and ______ in CHF or CKD for treatment of constipation due to electrolyte imbalances
PEG and Mag hydroxide
T/F?
Suppositories should be used as first line agents for dyssynergic defecation
False, used when oral agents are ineffective
Example of stimulant medications for constipation
Senna
Bisacodyl
What hormonal change in gut is responsible for decreased appetite in older adults?
Altered ghrelin secretion
Two screening tools for malnutrition and feeding problems in elderly
Mini-nutritional assessment ( 6 question, 89% sensitive, 82% specific) DETERMINE Checklist: Disease Eating Poorly Tooth Loss/Mouth Pain Economic Hardship Reduced Social Contact Multiple Medicines Involuntary Weight Loss/Gain Needs Assistance in Self- Care Elder Years Above Age 80
Differentiate esophageal vs oropharyngeal dysphagia based on symptoms
Esophageal - difficulty swallowing several seconds after initiating swallow, feeling food is stuck
Oropharyngeal - difficulty initiating swallow, regurgitation, aspiration, coughing/choking
All of the following are possible diagnosis of what symptom profile (solids/liquids, progressive/intermittent):
Esophageal stricture
Peptic stricture
Cancer
Solids ONLY + progressive symptoms
All of the following are possible diagnosis of what symptom profile (solids/liquids, progressive/intermittent):
Esinophilic esophagitis
Esophageal webs/rings
Vascular abnormality
Solids ONLY + intermittent symptoms
All of the following are possible diagnosis of what symptom profile (solids/liquids):
Achalasia
Esophageal spasm or contractile disorder
Functional disorder
Liquid and/or solid dysphagia
All of the following are possible diagnosis of what symptom profile:
Infectious esophagitis - HSV/candida
Medication induced - doxy, biphosphonates
Odynophagia + dysphagia
Name that condition:
Loss of normal peristalsis in distal esophagus and failure of LES relation with swallow
Progressive dysphagia with solids and liquids
Regurgitation of bland, undigested food or saliva
+/- chest pain, heart burn and difficulty burping
Achalasia
Functional dysphagia must have duration of ______ with symptom onset at least _____ prior to diagnosis and frequency of at least once weekly
Functional dysphagia must have duration of 3 months with symptom onset at least 6 months prior to diagnosis and frequency of at least once weekly
Diagnostic tests to consider for esophageal dysphagia
Barium swallow
Upper endoscopy/biospy
Esophageal manometry
Diagnostic tests to consider for oropharyngeal dysphagia
nasalendoscopy
videofluroscopy + manometry
Clinically significant weight loss
>/= 2 % in baseline body weight in 1 month >/= 5% decrease in 3 months >/= 10 % decrease in 6 months
T/F?
Elderly patients have ambiguous presentations for abdominal pain and should be imaged liberally.
True
Which of the following mesenteric ischemias (SMA embolus, SMA thrombosis, SMV thrombosis, or NOMI ischemia) have the following risk factors:
a.fib
valvular heart disease
dilated cardiomyopathy
SMA emobolus
Which of the following mesenteric ischemias (SMA embolus, SMA thrombosis, SMV thrombosis, or NOMI ischemia) have the following risk factors:
Atherosclerosis
Smoking
SMA thrombosis
Which of the following mesenteric ischemias (SMA embolus, SMA thrombosis, SMV thrombosis, or NOMI ischemia) have the following risk factors:
hypercoagulable
OC use
SMV thrombosis
What S&S would make you suspect mesenteric ischemia
out of proportion pain, N/V/D, postrprandial pain
Diagnosis of mesenteric ischemia
CT/angio
BW - acidosis
T/F?
Blood in urine can be a sign of AAA
True
What diagnostic test has the highest sensitivity for bowel obstruction?
CT abdo
All of the following are sequelae of what condition:
abscess, fistula, obstruction, perforation, sepsis, GI bleed
Diverticular disease
What is the most common cause of lower GI bleeding in older adults?
DIverticular disease
Conoloscopy or sigmoidoscopy is indicated ____ after resolution of diverticular symptoms to rule out _____
4-6 weeks
Carcinoma
True/False
PUD in elderly may present with the ABSENCE of abdominal pain
True
T/F?
Melena is the most common sign of PUD in the elderly?
True
What is the #1 cause of abdominal surgery in the elderly?
Acute cholecystitis
Posterior infarct is the most common location of MI that may present as abdominal pain. T/F?
False, inferior infarct is most common
T/F?
Normal BW can rule out AMI in elderly
False
T/F?
Abdominal rigidity is a reliable sign of visceral perforation in elderly
False
T/F?
Hyperplastic polyps have malignant potential on colorectal cancer screening
False, no malignant potential
What stool test is performed for bloody infectious diarrhea?
Ecoli
Severe diarrhea is classified according to 5 criteria for ANY duration. List the criteria.
Fever > 38.5 Bloody stool Systemic illness Hemodynamic instability >6 diarrhea/day for 5 days
What tests are indicated for severe diarrhea?
c. diff
O&P
culture
Moderate - mild diarrhea duration is ______ when no testing is reccomended
< 5 days
Earlier testing for infectious diarrhea is warrants if > 70 years, severe abdominal pain or querying c. diff. T/F?
True
Testing is reccomended if mild-moderate diarrhea is ongoing for ______
> 5 days
BW to consider for malnutrition
CBC protein/albumin CRP lipids electrolytes BUN/Cr
Why is it important to order CRP with albulim/prealbumin for malnourished individuals
Low albumin and prealbumin can occur with illness/inflammation. If CRP - then likely malnutrition
If pancreatitis is diagnosed in primary care or suspected, what is the next step?
Refer