Norton Part 4 Flashcards
what are the subtypes of squamous cell carcinoma
oral and verrucous (resemble large warts)
diagnosis of non melanoma skin cancer requires what
biopsy (shave, punch, incisional, or excisional)
to determine the presence or absence of invasive disease one must go how deep in a biopsy
mid dermis
if lymphadenopathy is present w/ squamous cell carcinoma what should be done
lymph node biopsy or FNA (fine needle aspiration)
a squamous eddy is seen in what?
squamous cell carcinoma
looks like a swirl
keratoacanthoma is what
a benign epithelial tumor that mat progress to squamous cell carcinoma
what appears suddenly on actinically-damaged skin, grow rapidly and spontaneously regress after a few months
keratoacanthoma
what does keratoacanthoma look like
red to flesh colored dome-shaped papule with a central crater filled with keratinous plug
what histological features are seen in keratoacanthoma
large, red, glassy squamoid cells
neutrophil micro abscesses common
eosinophils and lymphocytes are common in surrounding infiltrate
cellular atypia and mitoses uncommon
keratoacanthoma may BE what
well-diffentiated SCC
what is the most common malignancy
basal cell carcinoma
basal cell carcinoma is of what cells
pluripotent cells in the basal layer of the epidermis or follicular structures
basal cell carcinoma grows at what speed and how often does it metastasize
slow growing
rarely metastasizes
if neglected or inadequately treated what can basal cell carcinoma cause
local destruction and disfigurement
with proper therapy what is the prognosis of basal cell carcinoma
excellent
what are risk factors for basal cell carcinoma
UV radiation X-ray arsenic immunosuppression prior history of NMSC
basal cell carcinoma often presents with what
a non-healing lesion that bleeds
basal cell carcinoma is commonly found where
face, ears, scalp, neck, or upper trunk
what are the subtypes of basal cell carcinoma
nodular (most common)
superficial (second most common)
morphaeaform
other rare ones
what is the most common subtype of basal cell carcinoma
nodular
nodular basal cell carcinoma is most commonly found where
face (most common site)
superficial basal cell carcinoma is most commonly found where
trunk
nodular basal cell carcinoma presents how
waxy papule with central depression pearly appearance erosion, ulceration, or crusting bleeding with minor trauma rolled (raised) border translucency telangiectasia over the surface
superficial basal cell carcinoma presents how
slightly scaly papule or plaque
light red color
atrophic center with fine translucent micropapules on rim
