Normocytic Anemia

Question 1

Anemia of Chronic Dz vs Iron Deficiency Anemia:

• _____ Ferritin
• _____ TIBC

Answer 1

• Anemia of Chronic Dz = Norm/High Ferritin & LOW TIBC
• Iron Deficiency Anemia = LOW Ferritin & HIGH TIBC

Question 2

1 cc of blood loss = ___ cc of Crystalloid replacement

Answer 2

3

Question 3

Anemia of Chronic Dz Tx

Answer 3

• Tx underlying ET
• EPO
• Iron Supp
• Transfusions if HgB <7

Question 4

Anemia of CKD is due to

Answer 4

Decr EPO

Question 5

Anemia of CKD is sussy if there is renal insufficiency CrCl < ________mL/min

Answer 5

45

Question 6

Anemia of CKD Tx

Answer 6

EPO (Darbo)

Question 7

Aplastic Anemia definition

Answer 7

Normocytic anemia (non-hemolytic) d/t hematopoietic stem cell DO -> loss of blood cell precursors

Question 8

Aplastic Anemia vs Myelodysplastic Syndromes (MDS)

Answer 8

• Aplastic Anemia is the LOSS of normal hematopoietic stem cells
• MDS is the formation of ABNORMAL stem cells

Aplastic anemia is Normocytic
MDS is Macrocytic

Question 9

Aplastic Anemia Tx

Answer 9

• Hematopoietic Stem Cell Transplant
• Transplant CI -> Immunosuppression

Question 10

2 ABX that can trigger G6PD Deficiency Hemolysis

Answer 10

Bactrim
Macrobid (Nitrofurantoin)

Question 11

G6PD Deficiency Blood Smear

Answer 11

Heinz Bodies
Bite or Blister Cells

Question 12

G6PD Dx

Answer 12

Quantitative Assay for G6PD enzyme

Question 13

G6PD Tx

Answer 13

Blood Transfusion
Folic Acid Supp

Question 14

Sickle Cell is an AR Chromo 11 B-globin gene mutation that codes for Hb____

Answer 14

HbS

Question 15

Sickle Cell Dx

Answer 15

• HgB Electrophoresis
• Blood Smear (Target cells, Nucleated RBCs, Howell-Jolly bodies)

Question 16

Sickle Cell ABX

Answer 16

• Prophylactic oral PCN if 4mo-6yo
• 3rd gen ceph (Cefotaxime)