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Sleep Medicine > Normal Sleep & Variants > Flashcards

Normal Sleep & Variants Flashcards

1
Q

Main Neurotransmitter of wakefulness

A

Glutamate

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2
Q

Brainstem Nuclei for wakefulness (5)

A

Raphe nucleus (RN)
Locus ceruleus (LC)
Substantia nigra (SN)
Pedunculopontine tegmental nucleus (PPT)
Laterodorsal tegmental nucleus (LDT)

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3
Q

Brain regions for wakefulness (4)

A

Brainstem
Thalamus
Hypothalamus (Posterolateral nuclei)
Basal forebrain (BF)

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4
Q

Glutamate - Sleep or wake, Location & Action

A

Wakefulness. Reticular formation. Primary neurotransmitter of the ARAS, critical for cortical activation

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5
Q

Norepi - Sleep or wake, Location & Action

A

Wakefulness. NE, DA, and 5-HT project to cortex through dorsal or ventral pathways of ARAS. Inhibit VLPO during wake, activity decreased in NREM and inactivated in REM.

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6
Q

DA - Sleep or wake, Location & Action

A

Wakefulness. NE, DA, and 5-HT project to cortex through dorsal or ventral pathways of ARAS. Inhibit VLPO during wake, activity decreased in NREM and inactivated in REM.

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7
Q

5-HT - Sleep or wake, Location & Action

A

Wakefulness. NE, DA, and 5-HT project to cortex through dorsal or ventral pathways of ARAS. Inhibit VLPO during wake, activity decreased in NREM and inactivated in REM.

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Sleep Medicine (13 decks)

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