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Sleep Medicine > Neurotransmitters - Basic > Flashcards

Neurotransmitters - Basic Flashcards

1
Q

Main neurotransmitter of wakefulness

A

Glutamate

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2
Q

Glutamate - Wake or sleep promoting?

A

Wake

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3
Q

Norepi - Wake or sleep promoting?

A

Wake

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4
Q

Dopamine - Wake or sleep promoting?

A

Wake

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5
Q

5-HT - Wake or sleep promoting?

A

Wake

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6
Q

Histamine - Wake or sleep promoting?

A

Wake

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7
Q

Hypocretin - Wake or sleep promoting?

A

Wake

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8
Q

Orexin - Wake or sleep promoting?

A

Wake

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9
Q

Acetylcholine - Wake or sleep promoting?

A

Wake or sleep depending on location

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10
Q

GABA - Wake or sleep promoting?

A

Sleep

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11
Q

Galanin - Wake or sleep promoting?

A

Sleep

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12
Q

Adenosine - Wake or sleep promoting?

A

Sleep

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13
Q

Process S

A

Sleep…S for sleep

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14
Q

Process C

A

Wake

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15
Q

Glutamate - Stage?

A

Wake

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16
Q

GABA - Stage?

A

NREM

17
Q

ACh - Stage?

A

REM

18
Q

Glycine - Stage?

A

REM muscle atonia

19
Q

Main neurotransmitter of NREM?

A

GABA

20
Q

Main neurotransmitter of REM?

A

ACh

21
Q

Main neurotransmitter of REM muscle atonia?

A

Glycine

22
Q

Effect of amphetamines - Sleep / wake and mechanism?

A

Stimulant by promoting release of DA, 5-HT, and NE, & block re-uptake

23
Q

Effect of metylxanthines - sleep / wake and mechanism?

A

Stimulant by antagonizing AD

24
Q

Effect of Bupropion - wake / sleep and mechanism?

A

enhances DA and NE activity

25
Q

Effect of Benzo and mechanism?

A

Promote Sleep by increasing GABA, promote slow wave sleep

26
Q

Effect of typical antipsychotics - wake / sleep and mechanism?

A

Sleep by blocking DA receptors

Sleep Medicine (13 decks)

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