Normal Pregnancy, Antepartum Care - Moulton Flashcards

1
Q

what are some sex linked disorders?

Dx how?

A

DMD
Fragile X - #2 mental retards

Chorionic villus sampling or amniocentesis

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2
Q

Which anticoagulant crosses the placenta?

Which does not?

A

Coumadin

Heparin

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3
Q

What causes phocomelia?

A

Thalidomide

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4
Q

SAB or congenital malformations are as high as 50% in women who take what in 1st trimester?

A

Retinoids (accutane)

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5
Q

What levels of b-hCG and PAPP-A associated w/down’s?

What additional assessment can make this dx?

A

Elevated b-hCG and low PAPP-A

Nasal bone assessment to NT thickness (INCREASED)

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6
Q

When do leg cramps occur?

A

Last half of pregnancy

More frequent at night in calves

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7
Q

Crown rump length bw when can determine due date w/in 7 days?

A

6-11 weeks

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8
Q

How does Hct change in pregnancy?

Hb?

platelets?
Factors 7-10?

A

Dec 4-7%

Dec 1.5-2 by 30-34 wks

Slight decrease
Increase

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9
Q

Kick count can be done when?

Feel how many in 2 hour period?

Most active when?

A

28 weeks

10x

9pm-1am

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10
Q

What test is done at 20 weeks?

28 weeks?

35 weeks?

A

US

Screen for GD, RhoGAM if needed, admin Tdap

Screen for GrpB strep - treat in labor if +

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11
Q

When do you perform amniocentesis?

Chorionic villi sampling?

A

16-20 weeks

11 weeks, higher miscarriage rate

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12
Q

Radiation is dose dependent and what level of exposure carries NO risk?

A

Less than 5 rads

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13
Q

What is a reactive result for nonstress test (NST)?

A

2 accelerations of at least 15 beats above baseline lasting at least 15 seconds during 20 minutes of monitoring

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14
Q

Name some prenatal labs done at 1st visit

Laundry

A
CBC
type and screen for Rh
Syphilis
HepB surface Ag
HIV, gonorrhea, chlamydia 
DM
UA
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15
Q

What tests are done at prenatal office visits?

A
BP
BMI
Urine protein
Uterine size
Fetal HR
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16
Q

Give some AR disorder laundry

A

Tay-Sachs
Sickle cell
thalassemia
CF - most common in whites

17
Q

Contraction stress test is looking to establish what?

Give what?

What is a + test?

A

3 contractions in 10 min

Oxytocin

Late decelerations -> deliver baby

18
Q

Fetal hydration syndrome is due to what?

How do they look?

A

Diphenylhydantoin (Dilantin)

Craniofacial abnormalities, growth Restriction, mental deficiency, CV anomalies

19
Q

1st trimester screening includes what?

A

Maternal age
NT thickness (inc assoc w/chromosomal abnormalities)
B-hCG
PAPP-A

20
Q

Noninvasive prenatal testing cell-free fetal DNA occurs when?

Tests what?

For what conditions?

A

9-10 wks (also 1st/2nd trimester) in high risk populations

Trophoblastic cells

Trisomy 13, 18, 21 but NOT NTD

21
Q

Level above ____ IU/L considered positive?

A

25 - hCG

22
Q

What is the most common teratogen?

A

Alcohol

23
Q

When do prenatal office visits occur?

A

Every 4 weeks until 28 weeks
Every 2 from 28-36
Weekly until delivery

24
Q

What is Naegels rule?

Need what?

A

Take LMP, minus 3 months, add 7 days and add 1 year to get expected delivery date

Regular 28 day periods

25
Q

When to start folic acid supplementation?

Dose with no hx of NTD?

Dose w/Hx of NTD?

A

1 month before conception

0.4 mg

4 mg

26
Q

When is the most vulnerable stage for teratology?

A

Day 17 - 56 post conception (organogenesis)

27
Q

What 2nd trimester triple screen tests are used?

Quadruple?

A

B-hCG
Estriol
AFP

Same + Inhibin A

28
Q

Give some AD disorder laundry

A
Tuberous sclerosis
NF
PCOS
Muscular dystrophy 
Achondroplasia craniofacial synostosis
29
Q

Total score of 8-10 of the biophysical profile indicates what?

6?

4 or less?

A

Reassuring

Deliver if pt is at term

Nonreassuring, consider delivery

30
Q

What is gestational age?

A

of weeks bw 1st day of LMP and date of delivery